About this Research Topic
The perinatal period, here defined as the time from conception until one year after birth, is a high-risk period for harmful exposures to teratogenic medications, potentially causing short and/or long-term adverse effects on the pregnancy, embryo, fetus, newborn and/or developing child. Hence, research into “Drug Safety in the Perinatal Period” is essential to timely identify (neurobehavioral) teratogens, protect newborns from exposure to teratogenic risks and to provide reliable information to healthcare professionals and patients.
This Research Topic aims to publish insights related to safety aspects of all kinds of medications, including vaccines, biologicals and other innovative therapies, used in the perinatal period. We welcome varied contributions from Original Research to Review Articles, Clinical Trials, Study Protocols and Case Series. This Research Topic is open for manuscripts applying various types of research methods (also including qualitative research) and study designs and focusing on every stage of the lifecycle of a medication, ranging from preclinical and clinical research to post-marketing surveillance and real-world evidence, and regulations and policies related to maternal and fetal pharmacotherapy. Manuscripts may report on a wide variety of research “data”, including but not limited to in vitro data, placenta-perfusion models, clinical (lactation) data, real-world data from pregnancy registries, charts, or electronic health records, administrative data, population-based cohort data, in silico data / pharmacokinetic modelling (PBPK, PopPK), infant follow-up data, and policy-oriented data.
Keywords: Teratology, Lactation, Pharmacology, Pharmaco-epidemiology, Pharmacovigilance
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.