About this Research Topic
Natural enzymes have attracted great attention owing to their important biological functions and excellent catalytic abilities in executing diverse biologically relevant functions. However, the inherent drawbacks of natural enzymes, such as their susceptibility to loss of activity due to denaturation of the molecule or depolymerization of the subunits, as well as the difficulty of purification, storage, and recycling, have greatly limited their practical applications. Under such circumstances, nanozymes, which are nanomaterials with intrinsic enzyme-like activities, have become the most popular and promising artificial enzymes in the past decades owing to their highly stable structures, adjustable activities, functional diversities, recyclability, and feasibility in large-scale preparation. To date, diverse nanozymes have been explored for mimicking the activities of oxidoreductase, hydrolase, lyase, and isomerase. Accordingly, the applications of nanozymes are spread nearly all over every branch of frontier biology ranging from biosensing, and antibacterial/antiviral, to antitumor treatment.
To highlight the significant contributions of researchers worldwide, we propose a Research Topic on the recent development of “Design and bioapplication of nanozymes”. This Research Topic is committed to publishing recent progress, achievements, breakthroughs, challenges, and future directions in various designs of nanozymes, specially, studies and reviews focusing on their bioapplications are encouraged. It aims to reflect the frontiers of nanozymes, promote the specialisation of the discipline, and provide a good platform for experts, scholars and researchers dedicated to biochemistry.
We welcome original research and review articles on topics including but not limited to:
•Novel strategies for engineering nanozymes with improved catalytic activities
•Structural characterization and mechanistic investigation of nanozymes
•Design of smart nanozymes responsive to biological stimuli
•Nanozyme-based biosensing systems for detecting biomolecules
•Biomedical applications of nanozymes for theranostic purposes New concepts, breakthroughs, and translational potential of nanozymes
•Theoretical and experimental studies on nanozyme design and applications
To highlight the significant contributions of researchers worldwide, we propose a Research Topic on the recent development of “Design and bioapplication of nanozymes”. This Research Topic is committed to publishing recent progress, achievements, breakthroughs, challenges, and future directions in various designs of nanozymes, specially, studies and reviews focusing on their bioapplications are encouraged. It aims to reflect the frontiers of nanozymes, promote the specialisation of the discipline, and provide a good platform for experts, scholars and researchers dedicated to biochemistry.
We welcome original research and review articles on topics including but not limited to:
•Novel strategies for engineering nanozymes with improved catalytic activities
•Structural characterization and mechanistic investigation of nanozymes
•Design of smart nanozymes responsive to biological stimuli
•Nanozyme-based biosensing systems for detecting biomolecules
•Biomedical applications of nanozymes for theranostic purposes New concepts, breakthroughs, and translational potential of nanozymes
•Theoretical and experimental studies on nanozyme design and applications
Keywords: nanozymes, design, detection, sensor, therapy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
