The role of micronutrients and metabolic wastes in cellular molecular mechanisms is receiving increasing attention. These micronutrients and metabolites play key roles in cellular physiology as well as in disease states, especially at various levels of genetic information expression and functional realization. Their functions are particularly important in the regulation of gene expression, DNA repair, chromatin remodeling, RNA processing, and post-transcriptional modifications.
Micronutrients and metabolic wastes such as selenium, iron, and zinc not only play a role in core metabolic pathways, but also exert influence in the regulation of several other metabolic mechanisms. Recently, the role of these micronutrients in tRNA modification and DNA repair, as well as new findings on the interactions of metabolic wastes with immune metabolism have attracted our attention. Understanding how these molecular mechanisms interact to influence disease processes and cancer development and cancer regulation may help identify new biomarkers and potential therapeutic targets.
We would like to invite submissions from researchers worldwide to share the roles of micronutrients and metabolic wastes in molecular mechanisms, especially those recent studies that shed light on their interactions in genetic regulation, immune metabolism, and other metabolic regulatory mechanisms. These studies may help to reveal new targets in the disease process and provide new directions for clinical treatment.
Keywords:
Tumor metabolism, Immune microenvironment, Metabolic waste, Nutrients, Tumor microbiome, Iron metabolism, Cancer therapy, Ferroptosis
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
The role of micronutrients and metabolic wastes in cellular molecular mechanisms is receiving increasing attention. These micronutrients and metabolites play key roles in cellular physiology as well as in disease states, especially at various levels of genetic information expression and functional realization. Their functions are particularly important in the regulation of gene expression, DNA repair, chromatin remodeling, RNA processing, and post-transcriptional modifications.
Micronutrients and metabolic wastes such as selenium, iron, and zinc not only play a role in core metabolic pathways, but also exert influence in the regulation of several other metabolic mechanisms. Recently, the role of these micronutrients in tRNA modification and DNA repair, as well as new findings on the interactions of metabolic wastes with immune metabolism have attracted our attention. Understanding how these molecular mechanisms interact to influence disease processes and cancer development and cancer regulation may help identify new biomarkers and potential therapeutic targets.
We would like to invite submissions from researchers worldwide to share the roles of micronutrients and metabolic wastes in molecular mechanisms, especially those recent studies that shed light on their interactions in genetic regulation, immune metabolism, and other metabolic regulatory mechanisms. These studies may help to reveal new targets in the disease process and provide new directions for clinical treatment.
Keywords:
Tumor metabolism, Immune microenvironment, Metabolic waste, Nutrients, Tumor microbiome, Iron metabolism, Cancer therapy, Ferroptosis
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.