Drug Repurposing to Fight Resistant Fungal Species: Recent Developments as Novel Therapeutic Strategies

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ORIGINAL RESEARCH

Accepted on 24 Mar 2025

Combinations of posaconazole and tacrolimus are effective against infections with azole-resistant Aspergillus fumigatus

Eliane Vanhoffelen
Tine Van Win
Eva Van Braeckel
Agustin Reséndiz-Sharpe
Bruno P. A. Cammue
Katrien Lagrou
Karin Thevissen
Greetje Vande Velde

doi 10.3389/fcimb.2025.1550457

ORIGINAL RESEARCH

Published on 13 Mar 2025

Computational analysis of Ayurvedic metabolites for potential treatment of drug-resistant Candida auris

Mohibullah Shah
Mahnoor Zia
Iqra Ahmad
Muhammad Umer Khan
Hasan Ejaz
Maqsood Alam
Shahid Aziz
Umar Nishan
Hanna Dib
1 more
Suvash Chandra Ojha

doi 10.3389/fcimb.2025.1537872

633 views

ORIGINAL RESEARCH

Published on 26 Feb 2025

Synergistic antifungal effects and mechanisms of amantadine hydrochloride combined with azole antifungal drugs on drug-resistant Candida albicans

Xiuyun Li
Yuanyuan Zhi
Ximeng Duan
Xu Chen
Min Cui
Shicun Zheng

doi 10.3389/fcimb.2025.1455123

648 views

ORIGINAL RESEARCH

Published on 09 Dec 2024

Baicalin promotes β-1,3-glucan exposure in Candida albicans and enhances macrophage response

Yiyuan Pan
Zhaoling Shi
Yadong Wang
Feng Chen
Yue Yang
Kelong Ma
Wenqian Li

doi 10.3389/fcimb.2024.1487173

774 views

REVIEW

Published on 01 Nov 2024

Artificial intelligence in predicting pathogenic microorganisms’ antimicrobial resistance: challenges, progress, and prospects

Yan Li
Xiaoyan Cui
Xiaoyan Yang
Guangqia Liu

doi 10.3389/fcimb.2024.1482186

3,316 views
2 citations

ORIGINAL RESEARCH

Published on 15 Oct 2024

ProcCluster® and procaine hydrochloride inhibit the growth of Aspergillus species and exert antimicrobial properties during coinfection with influenza A viruses and A. fumigatus in vitro

Sarah König
Josefine Schroeder
Thorsten Heinekamp
Axel A. Brakhage
Bettina Löffler
Beatrice Engert
Christina Ehrhardt

doi 10.3389/fcimb.2024.1445428

2,308 views

OPINION

Published on 30 Sep 2024

Minocycline is a promising candidate as a combination therapy with caspofungin for drug-resistant Candida

Kazuhiro Itoh
Hiroshi Tsutani
Yasuhiko Mitsuke
Hiromichi Iwasaki

doi 10.3389/fcimb.2024.1452497

657 views

ORIGINAL RESEARCH

Published on 29 Aug 2024

Pythium insidiosum: an emerging pathogen that is easily misdiagnosed and given treatment as a fungus

Liuyang Hu
Xiulu Huang
Ngan Hung Yee
Huixia Meng
Li Jiang
Liang Liang
Xingchun Chen

doi 10.3389/fcimb.2024.1430032

2,134 views
1 citation

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Frontiers in Cellular and Infection Microbiology

Antibiotic Resistance and New Antimicrobial drugs

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Articles

Combinations of posaconazole and tacrolimus are effective against infections with azole-resistant Aspergillus fumigatus

Computational analysis of Ayurvedic metabolites for potential treatment of drug-resistant Candida auris

Synergistic antifungal effects and mechanisms of amantadine hydrochloride combined with azole antifungal drugs on drug-resistant Candida albicans

Baicalin promotes β-1,3-glucan exposure in Candida albicans and enhances macrophage response

Artificial intelligence in predicting pathogenic microorganisms’ antimicrobial resistance: challenges, progress, and prospects

ProcCluster® and procaine hydrochloride inhibit the growth of Aspergillus species and exert antimicrobial properties during coinfection with influenza A viruses and A. fumigatus in vitro

Minocycline is a promising candidate as a combination therapy with caspofungin for drug-resistant Candida

Pythium insidiosum: an emerging pathogen that is easily misdiagnosed and given treatment as a fungus

Frontiers in Cellular and Infection Microbiology

Antibiotic Resistance and New Antimicrobial drugs