About this Research Topic
Testicular cancer is the most common malignancy in adolescent and young men. Contemporary treatment modalities, including retroperitoneal lymph node dissection, systemic chemotherapy, and loco-regional radiotherapy have resulted in exceptional survival rates exceeding 95% in recent decades. Recent emphasis on patients survivorship in this young patient population has become an integral issue towards improving patient outcomes.
Improving cancer survivorship not only signifies advancements in treatment efficacy but also mitigating the consequential long-term risk associated with treatment burden. This can be achieved through improvements in patient selection, optimization of peri-operative care, refinements in treatment modalities, and incorporation of highly predictive biomarkers capable of risk stratifying patients and ultimately assist in decision making throughout treatment and surveillance.
The goal of this Research Topic is to highlight the knowledge gaps in the current management paradigm of testicular germ cell tumors, and discuss advancements in testicular care management. This includes a focus on improving peri-operative care, refinements in surgical techniques, dose de-escalation strategies for chemotherapy and radiation therapy, as well as potential role for novel biomarkers.
We invite submissions of Original Research, Reviews, Systematic Reviews, and Mini-Reviews on the following topics:
1: The current management approach to early-stage and advanced testicular cancer, with emphasis on treatment related burden and the limitations of current treatment modalities
2: Advancements in the peri-operative care pathways of testicular cancer patients
3: Refinements and advancements in surgical techniques for retroperitoneal lymph node dissection
4: Current chemotherapy and radiotherapy management protocols for early-stage testicular cancer and potential for dose de-escalation approaches
5: Potential role for novel biomarkers to improve selection and outcomes of testicular cancer patient
6: Ongoing clinical trials aimed at improving patient survivorship
Improving cancer survivorship not only signifies advancements in treatment efficacy but also mitigating the consequential long-term risk associated with treatment burden. This can be achieved through improvements in patient selection, optimization of peri-operative care, refinements in treatment modalities, and incorporation of highly predictive biomarkers capable of risk stratifying patients and ultimately assist in decision making throughout treatment and surveillance.
The goal of this Research Topic is to highlight the knowledge gaps in the current management paradigm of testicular germ cell tumors, and discuss advancements in testicular care management. This includes a focus on improving peri-operative care, refinements in surgical techniques, dose de-escalation strategies for chemotherapy and radiation therapy, as well as potential role for novel biomarkers.
We invite submissions of Original Research, Reviews, Systematic Reviews, and Mini-Reviews on the following topics:
1: The current management approach to early-stage and advanced testicular cancer, with emphasis on treatment related burden and the limitations of current treatment modalities
2: Advancements in the peri-operative care pathways of testicular cancer patients
3: Refinements and advancements in surgical techniques for retroperitoneal lymph node dissection
4: Current chemotherapy and radiotherapy management protocols for early-stage testicular cancer and potential for dose de-escalation approaches
5: Potential role for novel biomarkers to improve selection and outcomes of testicular cancer patient
6: Ongoing clinical trials aimed at improving patient survivorship
Keywords: Testicular cancer, Germ cell tumors, Seminoma, Non-seminoma, Retroperitoneal lymph node dissection, Cisplatin chemotherapy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
