Advances in Genomic surveillance of antimicrobial resistance in Low and Middle-Income Countries

Antimicrobial resistance (AMR) represents one of the most pressing public health threats globally, particularly in low and middle-income countries (LMICs) where healthcare resources are often limited. The capability to monitor and respond to AMR patterns is crucial for managing infections effectively and mitigating the spread of resistance. Genomic surveillance—utilizing advanced molecular techniques to study pathogens has emerged as a key strategy in understanding and addressing AMR. The evolving landscape of genomic technologies offers unprecedented opportunities to detect and track resistance mechanisms efficiently, providing essential insights for developing therapeutic and preventive measures. Until recently, genomic surveillance was a thing for the ivory towers but the recent COVID-19 pandemic unveiled it as a tool for routine applications in LMICs. In responding to the AMR threat, genomic surveillance is being applied in unique ways and circumstances in LMICs in a bid to drive innovation and capacity development.
This collection aims to showcase recent advances in genomic surveillance that can enhance the capability of LMICs to monitor, predict, and manage antimicrobial resistance. The primary focus is on integrating cutting-edge genomic technologies with existing health systems to provide a more comprehensive understanding of AMR dynamics. The potential of genomic surveillance lies not only in identifying existing resistance but also in predicting future trends and informing public health strategies. By highlighting innovative approaches and collaboration between researchers, healthcare providers, and policymakers, this collection seeks to empower LMICs in their battle against AMR. Contributions may include studies on the implementation of genomic surveillance programs, assessments of their cost-effectiveness, or reviews of policy impacts on resistance management. Ultimately, by bridging the technological divide, we can enhance the global response to AMR and facilitate equitable health outcomes.
We invite researchers to contribute original research articles, reviews, and case studies that address various aspects of genomic surveillance of AMR in LMICs. Specific themes of interest include:
• Implementation of genomic surveillance technologies in resource-limited settings.
• Integration of genomic data with national and international AMR monitoring networks.
• Cost-effectiveness and affordability of genomic tools.
• Policy and ethical considerations in deploying genomic surveillance.
• Case studies on successful AMR management through genomic approaches.
• Best case scenarios for implementing AMR in LMICs

Keywords: Genomic Surveillance, Antimicrobial Resistance (AMR), Low and Middle-Income Countries (LMICs), Public Health Genomics, Pathogen Genomics

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.