About this Research Topic
Evolutionary systems biology is a rapidly evolving field that combines concepts from evolutionary biology, ecology, genetics, and systems biology, among others. One of the central questions that evolutionary systems biology seeks to answer is how the genotype-phenotype relationship evolves over time, including the genetic mechanisms and gene expression patterns that drive biological adaptation. Gene evolution and mutation are essential components of this process and play a critical role in shaping the evolution of complex traits that underlie the diversity of life.
Understanding the mechanisms by which genes evolve can provide insights into the origin of new genes, the evolution of gene functions, their pathway interactions, and the processes that lead to the derivation of novel phenotypic traits. Various factors influence gene evolution, including mutation, recombination, natural selection, and genetic drift. Genetic mutations, such as point mutations, insertions, deletions or recombination events, can trigger evolutionary novelty or diversification, leading to functional variations that correspond to adaptation, fitness and speciation.
Genomic tools such as high-throughput DNA sequencing have shed new light on identifying the effects of natural selection that drive gene evolution across a wide range of organisms. Furthermore, statistical methods and computational algorithms help in examining the origin and evolution of genes extensively in the context of the gene regulatory relationships, genetic pathways interactions, and phylogenomics, revealing the genetic basis of adaptation and speciation.
This research topic seeks to explore the genetic mechanisms underlying gene evolution and mutation and their relevance to evolutionary systems biology. We welcome original research articles, review manuscripts, and methods articles on the following (but not limited to):
- Genetic mechanisms underlying the origin of new genes and their functional evolution
- Mechanisms shaping the evolution of the genetic code, including codon usage and their functional implications
- Genetic mechanisms underlying the evolution of gene expression and regulatory pathways
- Evolutionary adaptation to novel environments driven by genetic mutations
- Application of statistical and computational approaches to identify the genetic basis of adaptation and speciation
- Effects of gene mutations on protein structure and function, including diseases caused by mutations
By exploring the genetic mechanisms of gene evolution and mutations, we can gain a deeper understanding of evolutionary biology and the genetic basis of adaptation and diversification, with potential implications for future drug discovery and disease prevention.
Understanding the mechanisms by which genes evolve can provide insights into the origin of new genes, the evolution of gene functions, their pathway interactions, and the processes that lead to the derivation of novel phenotypic traits. Various factors influence gene evolution, including mutation, recombination, natural selection, and genetic drift. Genetic mutations, such as point mutations, insertions, deletions or recombination events, can trigger evolutionary novelty or diversification, leading to functional variations that correspond to adaptation, fitness and speciation.
Genomic tools such as high-throughput DNA sequencing have shed new light on identifying the effects of natural selection that drive gene evolution across a wide range of organisms. Furthermore, statistical methods and computational algorithms help in examining the origin and evolution of genes extensively in the context of the gene regulatory relationships, genetic pathways interactions, and phylogenomics, revealing the genetic basis of adaptation and speciation.
This research topic seeks to explore the genetic mechanisms underlying gene evolution and mutation and their relevance to evolutionary systems biology. We welcome original research articles, review manuscripts, and methods articles on the following (but not limited to):
- Genetic mechanisms underlying the origin of new genes and their functional evolution
- Mechanisms shaping the evolution of the genetic code, including codon usage and their functional implications
- Genetic mechanisms underlying the evolution of gene expression and regulatory pathways
- Evolutionary adaptation to novel environments driven by genetic mutations
- Application of statistical and computational approaches to identify the genetic basis of adaptation and speciation
- Effects of gene mutations on protein structure and function, including diseases caused by mutations
By exploring the genetic mechanisms of gene evolution and mutations, we can gain a deeper understanding of evolutionary biology and the genetic basis of adaptation and diversification, with potential implications for future drug discovery and disease prevention.
Keywords: evolution, genetics, gene mutation, genetic evolution
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
