About this Research Topic

Background

Biomarker research in dentistry is an emerging field that holds significant promise for transforming diagnostic and therapeutic approaches in oral health. Despite advancements in dental care, there remain substantial gaps in early detection and personalized treatment of oral diseases. Current research has identified various biomarkers, such as proteins, nucleic acids, and metabolites, that can be measured to indicate biological processes and disease states. Recent studies have shown the potential of saliva-based biomarkers in diagnosing conditions like periodontal diseases, caries, and oral cancers. However, the field still faces challenges in the efficient extraction and analysis of these biomarkers, and there is a need for more comprehensive studies to validate their clinical utility. Addressing these gaps could lead to more precise and individualized dental care, ultimately improving patient outcomes.

This research topic aims to delve into the potential of molecular signatures in dentistry, focusing on the identification, validation, and application of biomarkers in oral health. We seek to answer critical questions about the role of genetic and salivary biomarkers in diagnosing and treating dental diseases. By testing hypotheses related to the interplay between genetic factors and environmental influences, we aim to pave the way for personalized treatment strategies. Our objective is to gather a diverse range of studies that will contribute to a deeper understanding of how biomarkers can revolutionize dental diagnostics and therapeutics.

To gather further insights into the boundaries of biomarker research in dentistry, we welcome articles addressing, but not limited to, the following themes:
- Blood and Saliva-Based Biomarkers:
- Identification and validation of specific proteins, nucleic acids, and metabolites in saliva indicative of various oral conditions, such as pulp and periodontal diseases, caries, and oral cancers.
- Technological advancements and methodologies for the efficient extraction and analysis of salivary biomarkers.
- Genetic Markers in Dental Diseases:
- Exploration of genetic markers associated with endodontic disease, orthodontic problems, enamel defects, temporomandibular disorders, and their interplay with epigenetics.
- Insights into the interplay between genetic factors and environmental influences, to pave the way for personalized treatment strategies based on an individual's genetic profile.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Curriculum, Instruction, and Pedagogy
• Data Report
• Editorial
• General Commentary
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Curriculum, Instruction, and Pedagogy
• Data Report
• Editorial
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Policy Brief
• Review
• Study Protocol
• Systematic Review
• Technology and Code

Keywords: Biomarkers, Molecular Signatures in Dentistry

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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