Pathophysiology, Treatment and Rehabilitation of Neurodegenerative Diseases in Geriatric Population

With the development of an aging society, the prevalence of chronic diseases is gradually increasing in geriatric population. Neurodegenerative diseases are getting higher in the older adults, including Alzheimer’s disease, Parkinson’s disease, Multiple sclerosis, Amyotrophic lateral sclerosis and so on. It is reported that more than one billion people are affected by neurodegenerative diseases, and around seven million people worldwide die from these diseases each year. These can lead to increased rates of hospitalization and mortality, placing a serious burden on individuals as well as society. At present, neurological diseases have become the second leading cause of death worldwide. The pathological changes of the onset of neurodegenerative diseases are irreversible, and existing drug treatments can only slow down the development of the disease, so early detection and intervention are crucial to slow down the progression of the disease and delay the onset of neurodegenerative diseases.

This Research Topic aims at exploring the latest research progress in neurodegenerative diseases in elderly populations, including disease mechanisms, disease treatment and rehabilitation. The aim of this study is to understand the latest pathogenesis of neurodegenerative diseases and provide a theoretical basis for the treatment of the diseases. In addition, it aims to stay at the forefront of the latest therapeutic applications and rehabilitation protocols in the field, striving to significantly improve the quality of life for our aging population affected by neurodegenerative diseases.

Researchers are invited to contribute original research articles, reviews, mini-reviews, systematic reviews, clinical trials, case reports, perspectives, opinions, and study protocols pertinent to this article collection. Potential themes for the proposed Research Topic include but are not limited to:

• Research on the mechanism of neurodegenerative diseases
• The latest treatments for neurodegenerative diseases
• Rehabilitation treatment of neurodegenerative diseases
• Employing innovative digital technologies for the assessment and management of neurodegenerative diseases in older adults
• Motor control/motor learning and measurement in domains related to rehabilitation physiotherapy practice of neurodegenerative diseases in older adults