The Immune Evasion and Survival Mechanisms in Aquatic Organism Infections

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About this Research Topic

Submission deadlines

  1. Manuscript Submission Deadline 23 February 2025

  2. This Research Topic is still accepting articles.

Background

Bacterial and parasitic diseases present escalating challenges in aquaculture. Currently, antimicrobial agents and some environmentally unfriendly chemical drugs are often used to keep farmed fish free from bacterial and parasitic-related diseases which can lead to various consequences, mainly focus on resistant bacterial strains and compromise food safety. Therefore, it is important to improve secure strategies to prevent and control these diseases. Most aquatic pathogenic microbes exhibit robust immune evasion capabilities from host immune system. Their evasion mechanisms aiding their survival in the target organs are the key to mediating the pathogenesis of these pathogenic microbes. Understanding the underlying mechanisms that enable these aquatic pathogenic microbes to evade from host immune system will offer novel and useful knowledge to help construct efficient therapeutic strategies for the prevention and treatment of correlated diseases.

Aquatic animals mainly live in diverse environments such as ponds, lakes, streams, rivers, and wetland, the ecosystem of which is vastly more complex compared to those of terrestrial counterparts. Therefore, the causative pathogens species affecting aquatic animals, their adaptation mechanisms, and pathogenic mechanisms will significantly differ from those affecting mammal species. This Research Topic focuses on the evasion mechanisms and strategies employed by aquatic pathogens for immune evasion and host persistence.

We welcome high-quality Original Research articles, as well as Reviews that investigate and discuss the following sub-topics:
 Virulence factors or molecules of the aquatic pathogens involved in invasion, persistence, or survival in aquatic animals.
 Host-pathogen interactions or immune response to the aquatic bacterial and parasitic pathogens.
 Strategies for overcoming the host innate immune response of the aquatic pathogens.
 Mechanisms used by aquatic pathogens to evade the clearance mediated by the adaptive immune system.

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Keywords: Aquatic animals, Bacterial and Parasitic Pathogens, Immune Evasion, Host-pathogen Interactions, Immune Response

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