Apicomplexan parasites are a group of specialized intracellular parasitic protozoa, that can infect variety animals and human with medical and economic importance. Once inside the host cell, they obtain nutrients from the host to support their own metabolic processes, growth, and virulence. However, the prevention and control of these parasites currently face various challenges, such as drug resistance, relapse, and the need for higher dosages. Further research focused on elucidating the mechanism of metabolic pathways of parasites is required to find effective drug targets. The growth and virulence of intracellular parasites are heavily reliant on their metabolic pathways, making these pathways particularly attractive targets for antiparasitic interventions. Thus, addressing the mechanism of metabolic pathways of parasites can shed the light on the effective prevention and treatment of apicomplexan parasites.
Due to the absence of complete in-depth genomic analysis and limited means of genetic manipulation of most of the apicomplexan parasites, the details of the metabolic pathways remain unknown and the emerging research on metabolism is progressing slowly. The goal of this Research Topic is to demonstrate the potential metabolic pathways of apicomplexan parasites and to procure novel effective drug targets against parasites.
Original Research, Reviews and other types of research that related to metabolism of apicomplexan parasites will be welcome, but are not limited to:
1. Exploration of unveiled metabolic pathways in apicomplexan parasites.
2. Novel perspectives on targeting metabolic pathways for therapeutic interventions.
3. Recent discoveries in molecular components bridging metabolic pathways.
Keywords:
Apicomplexan, Protozoa, Metabolic Pathways, Drug targets
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Apicomplexan parasites are a group of specialized intracellular parasitic protozoa, that can infect variety animals and human with medical and economic importance. Once inside the host cell, they obtain nutrients from the host to support their own metabolic processes, growth, and virulence. However, the prevention and control of these parasites currently face various challenges, such as drug resistance, relapse, and the need for higher dosages. Further research focused on elucidating the mechanism of metabolic pathways of parasites is required to find effective drug targets. The growth and virulence of intracellular parasites are heavily reliant on their metabolic pathways, making these pathways particularly attractive targets for antiparasitic interventions. Thus, addressing the mechanism of metabolic pathways of parasites can shed the light on the effective prevention and treatment of apicomplexan parasites.
Due to the absence of complete in-depth genomic analysis and limited means of genetic manipulation of most of the apicomplexan parasites, the details of the metabolic pathways remain unknown and the emerging research on metabolism is progressing slowly. The goal of this Research Topic is to demonstrate the potential metabolic pathways of apicomplexan parasites and to procure novel effective drug targets against parasites.
Original Research, Reviews and other types of research that related to metabolism of apicomplexan parasites will be welcome, but are not limited to:
1. Exploration of unveiled metabolic pathways in apicomplexan parasites.
2. Novel perspectives on targeting metabolic pathways for therapeutic interventions.
3. Recent discoveries in molecular components bridging metabolic pathways.
Keywords:
Apicomplexan, Protozoa, Metabolic Pathways, Drug targets
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.