About this Research Topic
The goal of this Research Topic is to summarize recent advances in the field of organ crosstalk with the immune system and/or with other organs in the presence of an activated immune system.
We welcome the submission of Review articles (comprehensive, systematic, or mini format), Original Research articles describing basic, translational and/or clinical studies, Methods articles, and Perspective or Opinion articles.
The articles should be focused on, but not limited to, the following topics:
• Specific organ responses to an activated immune system in the context of trauma, musculoskeletal diseases, or regenerative scenarios
• Organ crosstalk in the context of trauma, musculoskeletal diseases, or regenerative scenarios
• Main players on organ crosstalk, e.g. cytokines, chemokines, proteins, receptors, cells, etc.
• Immunotherapeutic approaches to selectively target dysregulated immune responses in trauma, musculoskeletal diseases, or regenerative scenarios
• In vitro models, e.g. organ-on-chip, organoids, etc. to study organ crosstalk in a compromised immune scenario
• Animal models to study organ crosstalk in a compromised immune scenario
• Clinical relevance of organ crosstalk in the context of trauma, musculoskeletal diseases, or regenerative scenarios
Keywords: Organ crosstalk, Immune system, Trauma, Tissue Regeneration, In vitro models, In vivo models
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.