About this Research Topic
Extracellular vesicles (EVs) are pivotal in cell communication, encapsulating a diverse array of molecules like proteins, nucleic acids, and lipids. These vesicles range from 30 to 5,000 nm and are secreted by both prokaryotic and eukaryotic cells into the surrounding environment. Classified mainly into exosomes, microvesicles, and apoptotic bodies, EVs facilitate critical cellular functions affecting immunity, disease progression, and more. Investigations into EVs have recently expanded beyond mere cellular communication to their roles in modulating key processes of cell survival and death, challenging earlier research focused mostly on internal cell mechanisms and immediate extracellular stresses, such as pharmacological agents.
This Research Topic seeks to thoroughly examine how extracellular vesicles influence cell survival and death, shedding light on their potential to alter disease progression and treatment response. The aim is to discover novel biological insights that could lead to groundbreaking approaches in medical treatment through the strategic manipulation of EVs.
We invite contributions exploring the effects of EVs on:
o Various cell death pathways, including apoptosis, necroptosis, autophagy-induced cell death, ferroptosis, and pyroptosis.
o The dual role of EVs in promoting and inhibiting cell survival, particularly in cancer settings.
o The adjustments of cellular mechanisms in disease progression and therapeutic intervention facilitated by EVs.
o The influence of EVs on cell proliferation and metabolic processes.
We welcome a variety of article types such as Original Research, (Mini-)Reviews, Brief Research Reports, and Perspectives, aiming to broaden the scope of current understanding and foster interdisciplinary dialogue. A full list of accepted article types, including descriptions, can be found at this link.
This Research Topic seeks to thoroughly examine how extracellular vesicles influence cell survival and death, shedding light on their potential to alter disease progression and treatment response. The aim is to discover novel biological insights that could lead to groundbreaking approaches in medical treatment through the strategic manipulation of EVs.
We invite contributions exploring the effects of EVs on:
o Various cell death pathways, including apoptosis, necroptosis, autophagy-induced cell death, ferroptosis, and pyroptosis.
o The dual role of EVs in promoting and inhibiting cell survival, particularly in cancer settings.
o The adjustments of cellular mechanisms in disease progression and therapeutic intervention facilitated by EVs.
o The influence of EVs on cell proliferation and metabolic processes.
We welcome a variety of article types such as Original Research, (Mini-)Reviews, Brief Research Reports, and Perspectives, aiming to broaden the scope of current understanding and foster interdisciplinary dialogue. A full list of accepted article types, including descriptions, can be found at this link.
Keywords: extracellular vesicles, cell death, cell survival, apoptosis, ferroptosis, pyroptosis, necroptosis, autophagy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
