About this Research Topic
Many neurological diseases cause cognitive dysfunction. As demonstrated by previous studies, impairment of memory and other intellectual functions may be improved by many noninvasive neuromodulation therapies, including transcranial magnetic stimulation (TMS), transcranial direct-current stimulation (tDCS), transcranial alternating current stimulation (tACS), noninvasive vagus nerve stimulation, focused ultrasound (FUS) mediated blood-brain barrier opening, aroma therapy, light therapy, and multi-sensory gamma stimulation. Recently, these neuromodulation techniques have shown potential for improving cognitive performance and daily activity level, alleviating hippocampal atrophy, and preserving neuronal and synaptic density across multiple brain areas.
This Research Topic aims to explore new strategies for cognitive rehabilitation evoked by noninvasive neuromodulation treatments in patients with neurological diseases. We hope that original studies and reviews providing up-to-date information on the effects and mechanisms of noninvasive neuromodulation therapies on cognitive performance in patients with the neurological disease can facilitate the development of these techniques. The information includes what parameters are valid for a specific noninvasive neuromodulation therapy, what are the advantages and limitations of different therapies, what types of methods are sensitive to assess improvements in cognitive function, which cognitive domains tend to be improved, studies adopting different biomarkers to uncover relevant mechanism, and other directions.
We welcome submissions of Original Research, Reviews, Cohort Studies, and Randomized Controlled Trials (excluding case reports) supported by the journal to assess the effects and mechanisms of noninvasive neuromodulation therapies. These may focus on but are not limited to the following topics:
- Effects of one or more noninvasive neuromodulation therapy on cognitive performance in patients with neurological diseases (e.g., AD, PD, or Cerebrovascular disease)
- Comparing different noninvasive neuromodulation therapies
- Assessing changes in different cognitive domains
- Changes in behavioral functions (e.g., ADL or Behavioral and Psychological Symptoms of Dementia) when cognitive function is improved
- Biomarkers of blood or cerebrospinal fluid
- Mechanisms in brain function (activations, connections, networks) and structure
Please note that submissions based on results from only animal experiments will not be accepted.
Keywords: cognitive dysfunction, neurological diseases, noninvasive neuromodulation therapies, effects, mechanisms, neurorehabilitation
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.