About this Research Topic
Pancreatitis is a condition characterized by pancreas inflammation and can be categorized into acute, chronic, and autoimmune. Common causes of acute pancreatitis include alcohol abuse, gallstones, and hyperlipidemia. Acute pancreatitis can be classified into mild, moderate, and severe forms. Mild and moderate cases typically require conservative management, while severe cases may necessitate admission to the intensive care unit and intervention. Chronic pancreatitis can be caused by alcohol abuse, idiopathic factors (unknown cause), and sometimes genetic factors. Autoimmune pancreatitis is an inflammation of the pancreas from an autoimmune etiology.
Diagnosing severe acute pancreatitis is crucial due to the substantial mortality associated with severe cases. Early diagnostic markers, severity scoring, and various imaging techniques, including radiological and endoscopic methods, play key roles in the management of acute pancreatitis. Surgical intervention may also be necessary in severe cases. For chronic pancreatitis, effective pain management and addressing endocrine and exocrine insufficiency are essential. Additionally, controlling sugar levels and regular follow-ups are crucial for detecting the development of pancreatic cancer. Autoimmune pancreatitis mimics pancreatic cancer, posing a challenge for diagnosis. Pain management in autoimmune pancreatitis is an important aspect. Therefore, identifying novel early markers for the differential diagnosis of pancreatic cancer and autoimmune pancreatitis is crucial.
Despite significant advances in medical care, managing pancreatitis remains challenging. This Research Topic aims to explore the latest developments in understanding and addressing acute, chronic, and autoimmune pancreatitis, offering a platform for comprehensive discussions on diagnosis, and therapeutic interventions, ultimately leading to improved patient outcomes, reduced morbidity and mortality rates, and enhanced quality of life. Researchers are encouraged to submit original research articles, reviews, mini-reviews, systematic reviews, case reports, perspectives, and short communications as well as theoretical papers, opinions, and methods relevant to this article collection that will cover topics such as (but not limited to):
- Diagnostic advancements: novel biomarkers and imaging techniques to improve early and accurate diagnosis, facilitating timely intervention and reducing unnecessary invasive procedures in acute, chronic, and autoimmune pancreatitis
- Prognostic indicators and risk stratification: innovative approaches to identify prognostic markers and develop reliable scoring systems for assessing disease severity, predicting complications, and informing clinical decision-making in acute, chronic, and autoimmune pancreatitis
- Personalized and precision medicine: consideration of genetic factors and host response variability in tailoring treatments based on individual patient characteristics as well as patient perspectives, preferences, and experiences in the diagnosis and treatment decision-making in acute, chronic, and autoimmune pancreatitis
- Discussion of current therapeutic interventions: efficacy and safety of current therapeutic approaches, including fluid resuscitation, pain management, nutritional support, antimicrobial therapy, and enzyme supplementation in acute, chronic, and autoimmune pancreatitis
- Novel therapeutic approaches: emerging therapeutic strategies such as endoscopic interventions, minimally invasive techniques, and targeted drug therapies in acute, chronic, and autoimmune pancreatitis
- Multidisciplinary approaches: collaboration between diverse disciplines, including gastroenterology, surgery, radiology, critical care, and nutrition, to provide comprehensive and optimal care for patients with acute, chronic, and autoimmune pancreatitis
Diagnosing severe acute pancreatitis is crucial due to the substantial mortality associated with severe cases. Early diagnostic markers, severity scoring, and various imaging techniques, including radiological and endoscopic methods, play key roles in the management of acute pancreatitis. Surgical intervention may also be necessary in severe cases. For chronic pancreatitis, effective pain management and addressing endocrine and exocrine insufficiency are essential. Additionally, controlling sugar levels and regular follow-ups are crucial for detecting the development of pancreatic cancer. Autoimmune pancreatitis mimics pancreatic cancer, posing a challenge for diagnosis. Pain management in autoimmune pancreatitis is an important aspect. Therefore, identifying novel early markers for the differential diagnosis of pancreatic cancer and autoimmune pancreatitis is crucial.
Despite significant advances in medical care, managing pancreatitis remains challenging. This Research Topic aims to explore the latest developments in understanding and addressing acute, chronic, and autoimmune pancreatitis, offering a platform for comprehensive discussions on diagnosis, and therapeutic interventions, ultimately leading to improved patient outcomes, reduced morbidity and mortality rates, and enhanced quality of life. Researchers are encouraged to submit original research articles, reviews, mini-reviews, systematic reviews, case reports, perspectives, and short communications as well as theoretical papers, opinions, and methods relevant to this article collection that will cover topics such as (but not limited to):
- Diagnostic advancements: novel biomarkers and imaging techniques to improve early and accurate diagnosis, facilitating timely intervention and reducing unnecessary invasive procedures in acute, chronic, and autoimmune pancreatitis
- Prognostic indicators and risk stratification: innovative approaches to identify prognostic markers and develop reliable scoring systems for assessing disease severity, predicting complications, and informing clinical decision-making in acute, chronic, and autoimmune pancreatitis
- Personalized and precision medicine: consideration of genetic factors and host response variability in tailoring treatments based on individual patient characteristics as well as patient perspectives, preferences, and experiences in the diagnosis and treatment decision-making in acute, chronic, and autoimmune pancreatitis
- Discussion of current therapeutic interventions: efficacy and safety of current therapeutic approaches, including fluid resuscitation, pain management, nutritional support, antimicrobial therapy, and enzyme supplementation in acute, chronic, and autoimmune pancreatitis
- Novel therapeutic approaches: emerging therapeutic strategies such as endoscopic interventions, minimally invasive techniques, and targeted drug therapies in acute, chronic, and autoimmune pancreatitis
- Multidisciplinary approaches: collaboration between diverse disciplines, including gastroenterology, surgery, radiology, critical care, and nutrition, to provide comprehensive and optimal care for patients with acute, chronic, and autoimmune pancreatitis
Keywords: pancreatitis, acute pancreatitis, chronic pancreatitis, autoimmune pancreatitis, IgG 4-related disease, biomarker, CRP, osteopontin, APACHE, BISAP, endoscopic management, percutaneous catheter drainage, EUS-FNA, sepsis, necrosis, pseudocyst
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