About this Research Topic
World Breastfeeding Week (WBW) is celebrated annually in the first week of August, organized by the World Alliance for Breastfeeding Action (WABA), WHO and UNICEF, with the goal of promoting breastfeeding and its many benefits to mother and child such as protection from deadly diseases, and provision of essential nutrients.
WHO recommends exclusively breastfeeding babies for the first six months, and if possible continuing with supplemented breastfeeding for a further 1-2 years. However, only 44% of infants are exclusively breastfed from 0-6 months. In the modern day with many medications in use by mothers during pregnancy and postpartum the impact of pharmaceuticals on breastfeeding and consequently the child is a crucial area of study.
The goal of this Research Topic is to bring to the forefront critical research on breastfeeding from an obstetric and pediatric pharmacology perspective, exploring a range of research strategies involving in vitro, in vivo or computational techniques to address drug related issues associated with breastfeeding at early and later stages of drug development, highlighting diverse perspectives (regulatory or patient outlook) and encouraging interdisciplinary collaboration. In doing so, we aim to deepen understanding of the implications of drug use during lactation and breastfeeding on mother and child.
This Research Topic welcomes submissions that investigate breastfeeding from an obstetric pharmacology perspective, including but not limited to:
• Safety and efficacy of drugs in breastfeeding
• Preclinical and clinical pharmacokinetics and pharmacodynamics studies
• Mechanistic studies examining drug transfer through breast milk
• The impact of maternal medications on lactation and breast milk composition
• Neonatal pharmacokinetics and breast milk exposure
• Strategies for managing drug-related lactation concerns
• Innovative approaches to prevent drug related breastfeeding or lactation issues including systems biology modelling, machine learning, artificial intelligence, and robotics.
• The impact of pharmacogenomics on maternal use of drugs during breastfeeding and lactation.
• Addressing drug-related breastfeeding and lactation issues in early stages of drug development.
• Regulatory or patient perspectives on this topic
WHO recommends exclusively breastfeeding babies for the first six months, and if possible continuing with supplemented breastfeeding for a further 1-2 years. However, only 44% of infants are exclusively breastfed from 0-6 months. In the modern day with many medications in use by mothers during pregnancy and postpartum the impact of pharmaceuticals on breastfeeding and consequently the child is a crucial area of study.
The goal of this Research Topic is to bring to the forefront critical research on breastfeeding from an obstetric and pediatric pharmacology perspective, exploring a range of research strategies involving in vitro, in vivo or computational techniques to address drug related issues associated with breastfeeding at early and later stages of drug development, highlighting diverse perspectives (regulatory or patient outlook) and encouraging interdisciplinary collaboration. In doing so, we aim to deepen understanding of the implications of drug use during lactation and breastfeeding on mother and child.
This Research Topic welcomes submissions that investigate breastfeeding from an obstetric pharmacology perspective, including but not limited to:
• Safety and efficacy of drugs in breastfeeding
• Preclinical and clinical pharmacokinetics and pharmacodynamics studies
• Mechanistic studies examining drug transfer through breast milk
• The impact of maternal medications on lactation and breast milk composition
• Neonatal pharmacokinetics and breast milk exposure
• Strategies for managing drug-related lactation concerns
• Innovative approaches to prevent drug related breastfeeding or lactation issues including systems biology modelling, machine learning, artificial intelligence, and robotics.
• The impact of pharmacogenomics on maternal use of drugs during breastfeeding and lactation.
• Addressing drug-related breastfeeding and lactation issues in early stages of drug development.
• Regulatory or patient perspectives on this topic
Keywords: Breastfeeding, lactation, breast milk composition, drug safety, drug efficacy, drug transfer
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
