About this Research Topic
Understanding the intricate biology and behavior of CSCs is crucial for the development of effective cancer treatments. The multifaceted nature of CSCs demands a comprehensive understanding of their mechanisms and dynamics. Progress in techniques to identify and isolate CSCs combined with advances in molecular biology, genomics, and single-cell analysis, have enabled deeper investigations into the heterogeneity and plasticity of CSCs.
This Research Topic welcomes submissions that seeks to explore the latest advancements, methodologies, and discoveries in the field of CSCs. Submissions may consider, but are not limited to the following themes:
• The molecular signatures and signaling pathways that govern CSC behavior
• The tumor microenvironment's influence on CSCs
• Novel therapeutic strategies targeting CSC vulnerabilities
• Emerging technologies, such as organoid and patient-derived xenograft (PDX) models
We accept different article types including Original Research articles, Mini-Reviews, Brief Research Reports, and Perspectives. A full list of accepted article types, including descriptions, can be found at this link.
Please note: studies consisting solely of bioinformatic investigation of publicly available genomic/transcriptomic/proteomic data do not fall within the scope of the section unless they are expanded and provide significant biological or mechanistic insight into the process being studied.
Keywords: Cancer, Cancer Stem Cells, Stem Cells, Pluripotent Cells
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.