About this Research Topic
The clinical role of statins during anticoagulation for venous thromboembolism (VTE) is a matter of debate. While anticoagulant therapy remains the cornerstone of deep vein thrombosis (DVT) management, recent evidence suggests that adjunctive therapies with statins, commonly prescribed for their lipid-lowering effects and cardiovascular benefits, may play a role in improving patient outcomes. Some randomized trials and meta-analyses have shown that statins are effective at primary prevention of VTE. Statins may exert their beneficial effects in DVT through various pathways, including reducing inflammation, improving endothelial function, enhancing the fibrinolytic system and by inhibitions of platelet activation.
Considering the aforementioned, this Research Topic aims to address this association between statin use and venous thromboembolism, through:
-Original Research investigating the association between Statins use and VTE;
-Original Research investigating the impact of statin on blood clotting: clinical investigations; molecular investigations; in vitro and in vivo studies
-Case reports and Case series describing the role of statin during anticoagulation for VTE
-Reviews on the role of statins during anticoagulation for VTE
-Reviews on the mechanism by which statins affect blood clotting
Keywords: Statins, venous thromboembolism, pulmonary embolism, deep vein thrombosis, bleeding, coagulation, clotting factor, death
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.