Cardiovascular research has long focused on peripheral blood pressure measures, traditionally viewed as the primary indicator for diagnosing and managing hypertension. From ancient times, the arterial system was considered merely a conduit for blood, with little recognition of the central arteries' active role in cardiovascular health. Over the centuries, our understanding has evolved significantly, culminating in the modern recognition of central blood pressure and arterial stiffness as critical factors in the progression of cardiovascular diseases. Despite these advances, the predominant emphasis remains on peripheral assessments, leaving central hemodynamic factors less explored.
This Research Topic aims to refocus attention on the central aspects of hemodynamics in cardiovascular diseases by investigating the etiological role of arterial damage and its potential as a marker for the progression of preclinical atherosclerotic processes. The objective is to advance the diagnostic and therapeutic approaches targeting the central arterial functions, enhancing the accuracy and effectiveness of cardiovascular disease management.
To gather further insights within this context, we welcome contributions that explore a range of related topics, including but not limited to:
-Hypertension and Arterial Stiffness
-Diabetes and Arterial Stiffness
-Cardiometabolic Diseases and Arterial Stiffness
-Arterial Stiffness and Target Organ Damage
-Arterial Aging: from Endothelial Dysfunction to Vascular Stiffness
-Arterial Structure and Function in Vascular Aging
-Arterial Stiffness and Cognition
-Arterial Stiffness and Inflammation
-Methods of Analysis of Arterial Stiffness
These contributions may include original research articles, review papers, and methodological studies that offer new insights into the diagnostic and prognostic potential of central hemodynamic evaluations and their relationship with broader cardiovascular health outcomes.
Keywords: Hypertension, Arterial Stiffness, Wave Pulse Velocity, Central Blood Pressure, Diabetes, Cardiovascular Disease
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.