About this Research Topic
Historically, the large arteries were considered as "passive conductors" of the blood; they were involved in blood transportation and distribution. Before Christ, Egyptian and Chinese scholars described the importance of arterial pulse wave as part of the physical examination. The evolution of knowledge about the arterial system in the coming centuries leaded to access the peripheral blood pressure in the last years of the XVIX century. This method generated all the knowledge that guides the hypertension diagnosis and treatment until the current days. However, the data on the blood pressure continues centred at peripheral measures.
In the last twenty years, countless pathophysiological, epidemiological, and pharmacodynamic studies have demonstrated the important role of the central blood pressure and the arterial stiffness in the evolutive cardiovascular disease process. Arterial stiffness also constitutes an important independent factor that can predict future risk of cardiovascular events, it is an important indicator of vascular changes, and it is associated with cardiovascular mortality in various groups of patients with cardiometabolic diseases as well as general population. Arterial stiffness can be assessed by three ways: central blood pressure, augmentation index (AIx) and pulse wave velocity (PWV), being PWV recognized as main marker of the severity of vascular injury.
Therefore, understanding the etiologic role of the arterial damage in the cardiovascular disease development and its participation as risk marker for evolution of the preclinical atherosclerotic process is very important for research of the new diagnostic methods and management of vascular lesions. This Research Topic hopes to receive original articles and review papers on the diagnostic and prognostic of the central hemodynamic evaluation, beyond the treatment responses of this condition.
The themes that can be addressed are as follows: Hypertension and Arterial Stiffness, Diabetes and Arterial Stiffness, Cardiometabolic Diseases and Arterial Stiffness, Arterial Stiffness and Target Organ Damage, Arterial Aging: from Endothelial Dysfunction to Vascular Stiffness, Arterial Structure and Function in Vascular Aging, Arterial Stiffness and Cognition, Arterial Stiffness and Inflammation, Methods of Analysis of Arterial Stiffness.
In the last twenty years, countless pathophysiological, epidemiological, and pharmacodynamic studies have demonstrated the important role of the central blood pressure and the arterial stiffness in the evolutive cardiovascular disease process. Arterial stiffness also constitutes an important independent factor that can predict future risk of cardiovascular events, it is an important indicator of vascular changes, and it is associated with cardiovascular mortality in various groups of patients with cardiometabolic diseases as well as general population. Arterial stiffness can be assessed by three ways: central blood pressure, augmentation index (AIx) and pulse wave velocity (PWV), being PWV recognized as main marker of the severity of vascular injury.
Therefore, understanding the etiologic role of the arterial damage in the cardiovascular disease development and its participation as risk marker for evolution of the preclinical atherosclerotic process is very important for research of the new diagnostic methods and management of vascular lesions. This Research Topic hopes to receive original articles and review papers on the diagnostic and prognostic of the central hemodynamic evaluation, beyond the treatment responses of this condition.
The themes that can be addressed are as follows: Hypertension and Arterial Stiffness, Diabetes and Arterial Stiffness, Cardiometabolic Diseases and Arterial Stiffness, Arterial Stiffness and Target Organ Damage, Arterial Aging: from Endothelial Dysfunction to Vascular Stiffness, Arterial Structure and Function in Vascular Aging, Arterial Stiffness and Cognition, Arterial Stiffness and Inflammation, Methods of Analysis of Arterial Stiffness.
Keywords: Hypertension, Arterial Stiffness, Wave Pulse Velocity, Central Blood Pressure, Diabetes, Cardiovascular Disease
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