Frontiers | Novel Insights into Liver Injury: Mechanisms, Pathophysiology, and Therapeutic Strategies

Novel Insights into Liver Injury: Mechanisms, Pathophysiology, and Therapeutic Strategies

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ORIGINAL RESEARCH

Published on 21 Nov 2024

ADRB2 serves as a novel biomarker and attenuates alcoholic hepatitis via the SIRT1/PGC-1α/PPARα pathway: integration of WGCNA, machine learning and experimental validation

Li Song
Shuo Huang
Honghao Yan
Qing Ma
Qihan Luo
Jiang Qiu
Minxia Chen
Zongyuan Li
He Jiang
6 more
Ping Qiu

ADRB2 serves as a novel biomarker and attenuates alcoholic hepatitis via the SIRT1/PGC-1α/PPARα pathway: integration of WGCNA, machine learning and experimental validation

doi 10.3389/fphar.2024.1423031

795 views

ORIGINAL RESEARCH

Published on 08 Jul 2024

FGF21-dependent alleviation of cholestasis-induced liver fibrosis by sodium butyrate

Jing Yang
Lei Chen
Shan-Shan Zhao
Chuang Du
Yi-Zhe Fan
Hui-Xin Liu
Yongchun Li
Yong-Zhi Li

FGF21-dependent alleviation of cholestasis-induced liver fibrosis by sodium butyrate

doi 10.3389/fphar.2024.1422770

1,122 views
1 citation

ORIGINAL RESEARCH

Published on 28 Mar 2024

Comprehensive analysis of brain injury parameters in a preclinical porcine model of acute liver failure

Philipp Felgendreff
Seyed M. Hosseiniasl
Lisa Felgendreff
Bruce P. Amiot
Anna Minshew
Boyukkhanim Ahmadzada
Zhi Qu
Silvana Wilken
Ines Arribas Gomez
1 more
Casey N. Cook

Comprehensive analysis of brain injury parameters in a preclinical porcine model of acute liver failure

doi 10.3389/fmed.2024.1363979

1,518 views

ORIGINAL RESEARCH

Published on 26 Mar 2024

Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity

Yuping Yang
Weinan Yuan
Kun He
Chuangzhen Lin
Shenshen Du
Yanqi Kou
Biao Nie

Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity

doi 10.3389/fphar.2024.1366479

1,640 views
1 citation

REVIEW

Published on 20 Mar 2024

Immune regulation and therapeutic application of T regulatory cells in liver diseases

Ananya Ajith
Makram Merimi
Mandana Kazem Arki
Nikoo Hossein-khannazer
Mehdi Najar
Massoud Vosough
Etienne Marc Sokal
Mustapha Najimi

Immune regulation and therapeutic application of T regulatory cells in liver diseases

doi 10.3389/fimmu.2024.1371089

3,267 views

ORIGINAL RESEARCH

Published on 23 Feb 2024

Associations between one-carbon metabolism and valproic acid-induced liver dysfunction in epileptic patients

Jingwei Zhu
Zhe Wang
Xiaotong Sun
Dan Wang
Xinbo Xu
Liping Yang
Jiangdong Du
Zhimei Zhou
Yanhua Qi
Linfeng Ma

Associations between one-carbon metabolism and valproic acid-induced liver dysfunction in epileptic patients

doi 10.3389/fphar.2024.1358262

885 views
1 citation

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Frontiers in Medicine

Hepatobiliary Diseases

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Frontiers in Pharmacology
- Gastrointestinal and Hepatic Pharmacology
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