Research in the mathematical modeling and numerical simulation of biofluid flow and heat transfer in living biological tissues is pivotal for advancing our comprehension of various physiological processes and disease mechanisms. In the realm of liver blood and bile circulation, as well as cancer therapy methodologies like hyperthermia, precise and effective numerical methods enhanced with image processing methodologies are indispensable. These methodologies aid in forecasting intricate flow patterns, temperature dispersion, and thermal impacts within biological tissues, thereby facilitating the formulation of efficacious treatment strategies and the optimization of therapeutic results. The importance of numerical simulations lies in their capacity to enhance the design and assessment of diverse biomedical procedures and devices, thereby contributing significantly to progress in medical research and practice.
Continual advancements in advanced numerical and mathematical techniques are aimed at capturing the intricate interplay between biofluid dynamics and heat transfer phenomena in living tissues. Practices such as computational fluid dynamics (CFD), including finite element and finite volume analysis, and multiphysics modeling are extensively employed to emulate the complex geometry and behavior of biological systems. These practices enable researchers to examine the transient and nonlinear characteristics of bioheat transfer processes, incorporate tissue heterogeneity, and consider patient-specific parameters for personalized treatment planning. The amalgamation of sophisticated mathematical tools with experimental data enhances the precision and dependability of simulations, fostering more knowledgeable decision-making in clinical environments.
The primary objective of research in mathematical modeling and numerical simulation of biofluid flow and heat transfer within living biological tissues, with a specific focus on liver blood and bile circulation, as well as cancer therapy modalities such as hyperthermia, is to progress the comprehension of underlying physiological mechanisms and optimize treatment strategies. By merging theoretical modeling with computational simulations, this research strives to elucidate the intricate interplay between blood flow, heat transfer, and tissue responses concerning liver diseases and cancer treatments. The ultimate aspiration is to devise pioneering therapeutic approaches capable of efficiently targeting diseased tissues, mitigating adverse effects, and enhancing patient outcomes.
This call for participation beckons researchers and practitioners to explore various aspects associated with liver blood and bile circulation, cancer therapy methods encompassing hyperthermia, and alternative thermal strategies.
Topics of interest include, but are not limited to:
• The modeling of tumor response to thermal therapy
• The optimization of heat delivery mechanisms for cancer treatment
• The comprehension of the role of blood perfusion in thermal therapies
• Advanced numerical and mathematical methods, such as image processing based CFD methods, for simulating multi-physics problems appearing in mass and heat transfer in living tissues.
Researchers are encouraged to delve into these domains to deepen our comprehension of bioheat transfer processes in biological tissues and promote the field of medical biophysics.
Keywords:
biofluid flow, mathematical modeling, bio-heat transfer, thermal therapy, tumor dynamics, emerging cancer therapies
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
Research in the mathematical modeling and numerical simulation of biofluid flow and heat transfer in living biological tissues is pivotal for advancing our comprehension of various physiological processes and disease mechanisms. In the realm of liver blood and bile circulation, as well as cancer therapy methodologies like hyperthermia, precise and effective numerical methods enhanced with image processing methodologies are indispensable. These methodologies aid in forecasting intricate flow patterns, temperature dispersion, and thermal impacts within biological tissues, thereby facilitating the formulation of efficacious treatment strategies and the optimization of therapeutic results. The importance of numerical simulations lies in their capacity to enhance the design and assessment of diverse biomedical procedures and devices, thereby contributing significantly to progress in medical research and practice.
Continual advancements in advanced numerical and mathematical techniques are aimed at capturing the intricate interplay between biofluid dynamics and heat transfer phenomena in living tissues. Practices such as computational fluid dynamics (CFD), including finite element and finite volume analysis, and multiphysics modeling are extensively employed to emulate the complex geometry and behavior of biological systems. These practices enable researchers to examine the transient and nonlinear characteristics of bioheat transfer processes, incorporate tissue heterogeneity, and consider patient-specific parameters for personalized treatment planning. The amalgamation of sophisticated mathematical tools with experimental data enhances the precision and dependability of simulations, fostering more knowledgeable decision-making in clinical environments.
The primary objective of research in mathematical modeling and numerical simulation of biofluid flow and heat transfer within living biological tissues, with a specific focus on liver blood and bile circulation, as well as cancer therapy modalities such as hyperthermia, is to progress the comprehension of underlying physiological mechanisms and optimize treatment strategies. By merging theoretical modeling with computational simulations, this research strives to elucidate the intricate interplay between blood flow, heat transfer, and tissue responses concerning liver diseases and cancer treatments. The ultimate aspiration is to devise pioneering therapeutic approaches capable of efficiently targeting diseased tissues, mitigating adverse effects, and enhancing patient outcomes.
This call for participation beckons researchers and practitioners to explore various aspects associated with liver blood and bile circulation, cancer therapy methods encompassing hyperthermia, and alternative thermal strategies.
Topics of interest include, but are not limited to:
• The modeling of tumor response to thermal therapy
• The optimization of heat delivery mechanisms for cancer treatment
• The comprehension of the role of blood perfusion in thermal therapies
• Advanced numerical and mathematical methods, such as image processing based CFD methods, for simulating multi-physics problems appearing in mass and heat transfer in living tissues.
Researchers are encouraged to delve into these domains to deepen our comprehension of bioheat transfer processes in biological tissues and promote the field of medical biophysics.
Keywords:
biofluid flow, mathematical modeling, bio-heat transfer, thermal therapy, tumor dynamics, emerging cancer therapies
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.