About this Research Topic
Brain tumors are devastating diseases, accounting for a significant proportion of cancer-related mortality and morbidity in both adults and children. Over the past few years, we have witnessed dramatic progress in clinical treatment for brain tumors. This is largely due to advancements in surgical skills, a more reasonable and personalized approach to radiotherapy and chemotherapy, and continuously updated immune therapy methods that modulate the immune microenvironment or specifically target tumor cells. However, various factors affect brain tumor treatments. These include the blood-brain barrier, tumor heterogeneity, the tumor immune microenvironment, and so on. Consequently, it is worthwhile that research conducted in these fields, both pre- and clinical, should be shared with the larger scientific community to further improve the clinical treatment for brain tumors.
The Research Topic’s ambitions are to bring together new discoveries in the clinical treatment for brain tumors. Manuscripts consisting of surgical approaches, radiotherapy, chemotherapy, immunotherapy, and other therapies on brain tumors are welcomed. Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases that are not accompanied by validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this Topic section.
We welcome manuscripts in the form of Original Research and Review focusing on, but not limited to, the following sub-topic:
1) The advancements in surgical techniques, including updated operative routes, minimally invasive approaches, and image-guided navigation systems.
2) In vitro, ex vivo, and in vivo tumor-related models analyzing the tumor and immune microenvironment and response to targeted brain tumor therapies.
3) Fundamental experimental studies, pre-clinical, and clinical research on novel strategies of chemotherapy, radiotherapy, and/or immunotherapy.
The Research Topic’s ambitions are to bring together new discoveries in the clinical treatment for brain tumors. Manuscripts consisting of surgical approaches, radiotherapy, chemotherapy, immunotherapy, and other therapies on brain tumors are welcomed. Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases that are not accompanied by validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this Topic section.
We welcome manuscripts in the form of Original Research and Review focusing on, but not limited to, the following sub-topic:
1) The advancements in surgical techniques, including updated operative routes, minimally invasive approaches, and image-guided navigation systems.
2) In vitro, ex vivo, and in vivo tumor-related models analyzing the tumor and immune microenvironment and response to targeted brain tumor therapies.
3) Fundamental experimental studies, pre-clinical, and clinical research on novel strategies of chemotherapy, radiotherapy, and/or immunotherapy.
Keywords: brain tumor treatment, network, brain metastases, immunotherapy, radiation therapy, chemotherapy, neurosurgery
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
