Effects of Pathogen Parasitism on Host Metabolism in Aquaculture Animals

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About this Research Topic

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Background

In the process of aquaculture, farmed animals are often attacked by various pathogenic microorganisms, leading to various diseases. Metabolism constitutes an indispensable and important aspect of the growth and development of aquaculture animals, playing a crucial role in animal health. Some pathogens restrict the growth and development of hosts by affecting their metabolism process and even cause secondary infections, resulting in more serious economic losses. Studies have shown that pathogens such as Microspora, Reovirus, and Vibrio can affect glucose metabolism, lipid metabolism, amino acid metabolism, and energy synthesis of crustaceans. At the same time, the molting stage of crustaceans is hindered, abnormal synthesis of chitinase, melatonin and stratum corneum protein, the shell of crustaceans becomes soft, the immunity is decreased, the development is delayed, and a large number of deaths are caused by secondary infections. Fish pathogens (Aeromonas, Pseudomonas, Cryptocaryon, iridovirus) usually change the immune response mechanism in the body and regulate its defense ability by affecting the host metabolism process (TCA cycle, pyruvate metabolism, amino acid metabolism). Therefore, the metabolism pathway plays an important role in regulating host immune response and growth and development. The interaction between metabolic mechanism, immune defense and growth and development needs to be further explored, and the interaction between pathogen and host in the process of metabolism needs to be further clarified.

In this Research Topic, we aim to explore the influence of pathogens on the development and metabolism of aquaculture animals and the potential relationship between the two by using multi-omics analysis, molecular and immune biotechnology methods. This Research Topic will help to further explore the interaction between aquatic pathogenic microorganisms and their hosts and provide strategies for the treatment and prevention of aquaculture animal diseases from the perspective of metabolism.

The Research Topic encourages researchers to submit articles highlighting the interactions between pathogens and aquaculture animals. We welcome Original Research, Reviews, and Methods related to the topic, including but not limited to the following subtopics:
- Metabolism mechanism of bacteria, viruses, parasites and other pathogens in aquaculture animals
- Effects of pathogens on glucose metabolism, lipid metabolism and energy synthesis in aquaculture animals
- Interaction and relation of metabolism and immune response between aquatic pathogens and host
- Prevention strategy of aquatic diseases based on metabolism pathway
- Influence of metabolic pathways on the growth and development of pathogens and hosts in aquaculture animals

Keywords: aquaculture animals, metabolism, pathogen parasitism, immune defense, growth and development, interaction

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