Cancer in Domestic, Exotic and Wild Animals: New Horizons in Tumorigenesis, Diagnosis, Prognosis and Therapeutics through Comparative Oncology

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About this Research Topic

Submission deadlines

  1. Manuscript Submission Deadline 31 July 2024 | Manuscript Extension Submission Deadline 31 December 2024

Background

Significant progress has been made in last years, understanding cancer biology, making way for more accurate and early diagnoses and increasingly specific and decisive therapeutic treatments. Furthermore, scientific advances in identifying increasingly sophisticated prognostic markers have enabled veterinarians to predict the course of neoplastic diseases, improving the overall quality of clinical approaches and outcomes for animals with cancer.
On the therapeutic front, novel treatment modalities and therapeutic interventions have emerged, offering hope for enhanced survival rates and improved quality of life for domestic and exotic animals.

In support of these scientific advances and the fundamental and interesting results of recent years, there have also been studies carried out in a comparative form, even with the human species, on the biology of many tumor forms, increasingly strengthening the importance of scientific approaches aimed at a “One Health” type evaluation also in the field of oncology, recognizing the close comparative connections between human, animal, and environmental health. Studying cancer in different animal species, including domestic, exotic, and wild animals, can provide valuable information with broad implications.
Recently, tumor-resistant animals such as naked mole rats, blind mole rats, elephants, and whales have been also attracting attention. The tumor-resistant mechanisms in these animals have a possibility to apply anti-cancer treatment in humans and the other domestic or exotic animals as well. Thus, comparative oncology in tumor-predisposed, such as dogs and cats, and tumor-resistant animals explores the commonalities and differences between human and animal tumors, contributing to developing new diagnostic methods, therapies and prevention techniques that advance both human and veterinary medicine.

This Research Topic with its seven research themes creates an interesting comparative meeting point in the oncology field, representing a new crossroad between veterinary science, oncology and wildlife and environmental conservation. We aim to create a new channel to share increasingly cutting-edge scientific knowledge and identify new diagnostic, therapeutic and preventive methods in this still very unexplored world of multispecies comparative oncology research. Our aim is thus to bring together experts from various fields of oncology research, such as veterinary medicine, human medicine, comparative oncology, molecular biology, wildlife conservation, and environmental sciences, to share insights, programs and results, aimed at reducing and eliminating exogenous and endogenous causal factors, predisposing and assisting oncological disease in animals and humans. Among the objectives, new forms of collaboration will also be stimulated and promoted to identify innovative ideas that benefit animals, humans and ecosystems globally, addressing the distinct challenges and perspectives of cancer management in different species.

We encourage submissions of original research, epidemiological studies, reviews and case reports presenting comparative oncology findings in the tumorigenesis, diagnosis, prognosis and treatment of cancer with particular attention to their application to domestic, exotic and wild animals, including cancers in endangered species. Research regarding tumor-resistant animals such as naked mole rats, blind mole rats, elephants, and whales, are also welcome.

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Keywords: Animals, tumors, Human cancers, One health, Tumorigenesis, Comparative pathology, Molecular oncolgy in animals, Oncology, domestic, exotic, wildlife, pets, multispecies, comparative oncology

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