About this Research Topic
Many patients who suffer from inborn error of immunity are prone to infection. In certain circumstances, it is life-threatening. As we know, T cells play a vital role in the defense of intracellular bacterial and viral infection. Memory T cells can protect them from secondary infection. It is urgent to figure out whether the development of T cells and the formation of memory T cells are impaired in these patients. An in-depth study of the characteristics and molecular mechanisms of T cells will enable us to better understand the nature of immunological memory and provide insights into both basic T-cell biology and translational immunotherapy.
Viral infection is a major threat to public health, antigen-specific T cells play a crucial role in antiviral immunity. Developing a vaccine that can efficiently induce memory T cell response is a key strategy for preventing virus infection. However, factors that are important for the differentiation of effector and memory T cells remain largely unknown. Many patients who suffer from inborn error of immunity are prone to viral infection, they are angels with broken wings, who are ideal models for studying the important factors that contribute to robust memory T cell formation. Deciphering the Memory T cell response in Inborn Error of Immunity could enable us to find a way to get robust T cell immunological memory, which is critical for vaccine immunization.
We welcome Original Research, Reviews, Mini Reviews, and Perspective articles on themes and factors that are important for T cell development and memory T cell formation.
Topic editor Associate Prof. Emmanuel Enoch Dzakah is employed by bioGenous Biotechnology, Inc. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Viral infection is a major threat to public health, antigen-specific T cells play a crucial role in antiviral immunity. Developing a vaccine that can efficiently induce memory T cell response is a key strategy for preventing virus infection. However, factors that are important for the differentiation of effector and memory T cells remain largely unknown. Many patients who suffer from inborn error of immunity are prone to viral infection, they are angels with broken wings, who are ideal models for studying the important factors that contribute to robust memory T cell formation. Deciphering the Memory T cell response in Inborn Error of Immunity could enable us to find a way to get robust T cell immunological memory, which is critical for vaccine immunization.
We welcome Original Research, Reviews, Mini Reviews, and Perspective articles on themes and factors that are important for T cell development and memory T cell formation.
Topic editor Associate Prof. Emmanuel Enoch Dzakah is employed by bioGenous Biotechnology, Inc. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Keywords: Memory, T cell, Inborn Error of Immunity, Viral infection, Primary immunodeficiency disease
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