About this Research Topic
Surprisingly little is known about the importance of membrane homeostasis to the overall cellular physiology. Even though defects in membrane properties (thickness, fluidity, lipid packing, curvature, and surface charge) have been implicated in various metabolic disorders, homeostasis of membrane bilayer remains a relatively understudied and underappreciated aspect of cell biology. However, recent technological advancements in mass spectrometry have been a revolutionary shift in our understanding of the types and roles of lipid species that play a crucial role in cellular function. The lipidomics platform will serve as a fundamental tool for identifying potential lipid biomarkers crucial for diagnosing human diseases. The portfolio of the current research topic will encompass all aspects of membrane lipid biology that play a role in defining cellular processes.
This collection aims to explore the comprehensive biology of membrane lipids and their pivotal role in defining various physiological processes. We are particularly interested in:
• Membrane heterogeneity
• Membrane homeostasis
• Membrane lipid composition and fluidity
• Protein-lipid interactions
• Lipid transport and metabolism
• Fatty acid metabolism
• Dietary lipids
We welcome Original Research articles, Reviews, and Mini-reviews papers as well as Methods, and Hypothesis and Theory articles. A full list of accepted article types, including descriptions, can be found at this link.
Keywords: Membrane homeostasis, Lipid metabolism, Lipidomics, Lipid composition, Fatty acids
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.