About this Research Topic
The urgency to find alternatives to antibiotics, due to the increasing figures of antibiotic resistance, is accelerating efforts to harness and explore these bio-nanoparticles. Recent advances in phage-virus hybrids, as well as phage protein engineering (e.g., capsid, tail, peptide, or enzyme), have broadened their applications to various industrial uses.
The goal of this research topic is to offer a comprehensive understanding of the bacteriophages’ potential, the challenges, and implications for revolutionizing the landscape of antibacterial and anticancer applications, with a strong emphasis on both in-vitro and in-vivo studies.
Therefore, this topic aims to disseminate cutting-edge research on antibacterial and anticancer therapies, stimulate discussion and advance our understanding on bacteriophages and phage-engineered products in clinical microbiology.
We encourage the submission of original research articles, reviews, mini-reviews, and methods that collectively cover a wide spectrum of subtopics, including, but not limited to:
1. Targeted Therapeutic Applications of Bacteriophages Against Antibiotic-Resistant Bacterial Strains
2. Engineering Bacteriophages for Enhanced Antibacterial Efficacy: A Molecular Approach
3. Exploring Bacteriophage-Derived Products for Antibacterial Coatings in Medical Devices
4. Phage-Based Approaches for Combating Biofilm-Associated Antibiotic Resistance
5. Bacteriophages as Precision Medicine: Tailoring Therapies for Antibiotic-Resistant Infections
6. Phage-Engineered Nanoparticles for Targeted Antibacterial Drug Delivery
7. Bacteriophages in Cancer Therapy: Selective Targeting of Tumor-Associated Bacteria
8. Phage-Induced Modulation of Tumor Microenvironment for Enhanced Anticancer Effects
9. Development of Bacteriophage-Loaded Hydrogels for Localized Antibacterial and Anticancer Treatment
10. Genetic Engineering of Bacteriophages for Synergistic Antibacterial and Anticancer Activity
11. Bacteriophage-Mediated Immunomodulation in Anticancer Therapy
12. Phage-Engineered Antibacterial and Anticancer Vaccines: A Dual-Action Strategy
13. Bacteriophage-Mimicking Nanoparticles for Antibacterial and Anticancer Applications
14. Combinatorial Approaches: Integrating Bacteriophages with Conventional Antibiotics in Anticancer Treatment
15. Bacteriophage-Targeted Therapy for Simultaneous Antibacterial and Anticancer Effects
Keywords: Bacteriophage Therapy (In-vitro and In-vivo), Phage Engineered Products, Endolysins and Depolymerases, Industrial Applications (Vaccines-Aquaculture-Bio-Pharmaceuticals), Clinical Applications for Antibiotic Resistance and Cancer, Antibioflim
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.