About this Research Topic
Neurodegenerative disorders (NDDs) have a profound impact on millions of individuals worldwide. These disorders manifest in various regions of the brain, leading to the gradual loss of nerve cell function and eventual cell death. While certain treatments can mitigate physical and mental symptoms associated with NDDs, their progression cannot currently be halted and no cures are known. NDDs commonly present with neuropsychiatric symptoms that may serve as underlying indicators of neurobiological changes during the prodromal phase. For instance, fatigue is more frequently observed in multiple sclerosis or Parkinson’s disease (PD), suggesting a potential biological basis for such symptoms. Neuropsychiatric symptoms may also be attributed to psychosocial factors that arise as a response to the challenges posed by NDDs. Individuals with PD, commonly experience social anxiety due to concerns about being negatively perceived in public, leading to social withdrawal from social interactions. Additionally, the use of the treatments for NDDs may further exacerbate neuropsychiatric symptoms. In the case of PD, dopamine agonist therapy has been linked to impulse control disorders, making it crucial for healthcare professionals to provide counseling about such risks to patients who are initiated on this treatment.
It has been known that the emergence of NDDs has had a profound impact on the well-being of patients, as neuropsychiatric symptoms associated with these conditions severely diminish their quality of life and place a considerable burden on their caregivers. Nevertheless, the coexistence of similar symptoms can complicate the diagnosis of mental disorders within the context of these diseases. Consequently, there is a critical necessity for the evaluation and proactive management of the neuropsychiatric symptoms experienced by individuals with NDDs in order to alleviate the distressing consequences and minimize the adverse effects on their overall condition.
The objective of this Research Topic is to explore practical strategies for effectively managing neuropsychiatric issues, with the aim of assisting clinicians in addressing the insufficient recognition and treatment of these frequently overlooked and inadequately confronted symptoms. We encourage the submission of data derived from basic research, clinical studies, and intervention studies focusing on neuropsychiatric in patients with NDDs across various fields, including neuroscience and psychiatry.
We highly encourage addressing specific themes that encompass, but are not limited to, the following:
• In-depth exploration of the neural circuitry, genetics, epigenetics, and developmental aspects relevant to identifying more effective treatment strategies for neuropsychiatric symptoms in NDDs.
• Comprehensive examination of the impact of neuropsychiatric syndromes on the diagnosis of NDDs.
• Evaluation of transdiagnostic approaches to understanding and managing neuropsychiatric symptoms across NDDs.
We warmly invite manuscripts centered around investigating the spectrum, facilitating diagnosis, or unveiling the underlying pathophysiology of neuropsychiatric symptoms in NDDs.
It has been known that the emergence of NDDs has had a profound impact on the well-being of patients, as neuropsychiatric symptoms associated with these conditions severely diminish their quality of life and place a considerable burden on their caregivers. Nevertheless, the coexistence of similar symptoms can complicate the diagnosis of mental disorders within the context of these diseases. Consequently, there is a critical necessity for the evaluation and proactive management of the neuropsychiatric symptoms experienced by individuals with NDDs in order to alleviate the distressing consequences and minimize the adverse effects on their overall condition.
The objective of this Research Topic is to explore practical strategies for effectively managing neuropsychiatric issues, with the aim of assisting clinicians in addressing the insufficient recognition and treatment of these frequently overlooked and inadequately confronted symptoms. We encourage the submission of data derived from basic research, clinical studies, and intervention studies focusing on neuropsychiatric in patients with NDDs across various fields, including neuroscience and psychiatry.
We highly encourage addressing specific themes that encompass, but are not limited to, the following:
• In-depth exploration of the neural circuitry, genetics, epigenetics, and developmental aspects relevant to identifying more effective treatment strategies for neuropsychiatric symptoms in NDDs.
• Comprehensive examination of the impact of neuropsychiatric syndromes on the diagnosis of NDDs.
• Evaluation of transdiagnostic approaches to understanding and managing neuropsychiatric symptoms across NDDs.
We warmly invite manuscripts centered around investigating the spectrum, facilitating diagnosis, or unveiling the underlying pathophysiology of neuropsychiatric symptoms in NDDs.
Keywords: Neuropsychiatry, neuropsychiatric symptoms, neurodegenerative disorders, mental disorders
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
