MicroRNAs as New Players in Endocrinology

MicroRNAs are non-coding RNAs that regulate developmental and physiological events by modulating gene expression, primarily at the post-transcriptional level. Several lines of evident suggest that microRNAs are major players in Endocrinology. First, microRNAs have hormone-like activities. They can be secreted from cells, enter circulation, reach target cells to regular their activities. Second, microRNAs regulate hormone secretion. Third, they modulate receptors and signaling networks that mediate the functions of hormones, growth factors, and cytokines. Finally, hormones have been reported to regulate the expression level of microRNAs.

This Research Topic aims to provide an updated overview of microRNA and their function and regulation in the endocrine system. We welcome reviews, primary research articles, and technical notes that are related to the following topics:

• MicroRNA biogenesis and mechanisms of gene regulation by microRNAs
• MicroRNA secretion and detection in circulation
• Role of microRNAs in regulating hormones production and secretions
• Modulation of intracellular signaling pathways by microRNAs
• Role of hormones in regulating microRNA secretion