About this Research Topic
Urinary tract infections (UTIs) are among the most common bacterial infections worldwide, affecting millions of individuals annually. Unfortunately, inappropriate and excessive use of antibiotics has led to the emergence of resistant strains of uropathogens, making treatment more difficult. The number of multi-drug or pan-drug resistant bacteria isolated from UTIs has increased alarmingly in recent years. This rise in resistance has significant implications for public health, as it can lead to long-term infections, increased healthcare costs, and even life-threatening complications. Traditional diagnostic methods, such as urine culture and antibiotic susceptibility testing, remain crucial in identifying the bacterial strain and determining its resistance profile. However, methods other than culture, such as polymerase chain reaction (PCR), biosensor-based detection methods, and next-generation sequencing, are becoming valuable tools for rapidly diagnosing and detecting resistance genes. UTI treatment plans may include antibiotics, combination therapies, or even non-antibiotic interventions. Healthcare professionals must emphasize the importance of good antibiotic stewardship, ensuring their correct use to minimize the development of further resistance.
This Research Topic aims to provide readers with information about trends of resistance in bacterial strains causing UTI, their AMR pattern, the impact of applied antibiotic therapy on outcomes of UTI, an overview of AMR and Urinary Tract Infections within and outside critical care with a global vision, identify potential solutions to prevent the spread of antimicrobial resistance, early and rapid diagnosis including the use of non-culture methods, epidemiological issue related to UTI and future initiatives on how to combat AMR, discuss opportunities concerning AMR and UTI when modifiable factors exist.
By understanding the underlying factors contributing to the increase in drug resistance in uropathogens, using advanced diagnostic techniques, and implementing appropriate treatment strategies, we can combat this disturbing trend and maintain the effectiveness of antibiotics in treating UTIs. In this Topic, we welcome the submission of Original Research articles, Mini-Reviews, Clinical Trials, Case Reports, and Brief Research Reports focusing on the abovementioned UTI topics.
This Research Topic aims to provide readers with information about trends of resistance in bacterial strains causing UTI, their AMR pattern, the impact of applied antibiotic therapy on outcomes of UTI, an overview of AMR and Urinary Tract Infections within and outside critical care with a global vision, identify potential solutions to prevent the spread of antimicrobial resistance, early and rapid diagnosis including the use of non-culture methods, epidemiological issue related to UTI and future initiatives on how to combat AMR, discuss opportunities concerning AMR and UTI when modifiable factors exist.
By understanding the underlying factors contributing to the increase in drug resistance in uropathogens, using advanced diagnostic techniques, and implementing appropriate treatment strategies, we can combat this disturbing trend and maintain the effectiveness of antibiotics in treating UTIs. In this Topic, we welcome the submission of Original Research articles, Mini-Reviews, Clinical Trials, Case Reports, and Brief Research Reports focusing on the abovementioned UTI topics.
Keywords: UTI, AMR, stewardship, new treatment strategies, UPEC, urinary track pathogens
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
