Engineering Nanocarriers for Biomedical Imaging and Therapy

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About this Research Topic

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Background

Nanotechnology has ushered in a profound impact on biomedical science. Nanocarriers, engineered with precision in nanometer dimensions, have emerged as critical tools in biomedical imaging and therapy. These carriers, often made of biocompatible materials such as lipids, polymers, or proteins, enable the targeted delivery of drugs and imaging agents at the nanoscale level. Their nanometer size allows for efficient cellular and sub-cellular interactions, hence enhancing payload delivery and efficacy. Furthermore, these nanocarriers can be tailored to respond to specific stimuli, such as pH or temperature, ensuring controlled payload release within the body. The combination of engineering, chemistry, and medicine in nanocarrier research offers great potential for personalized therapies, making it a rapidly growing area of study in modern medicines.

Lack of precision in drug delivery presents a significant hurdle in the advancement of biomedical therapies and imaging. Engineered nanocarriers represent a cutting-edge solution to this challenge. These microscopic structures, meticulously designed and tailored, can encapsulate therapeutic/imaging agents and navigate complex biological barriers with accuracy. The problem, however, lies in perfecting these carriers to ensure they reach specific cells or tissues efficiently. This Research Topic "Engineering Nanocarriers for Biomedical Imaging and Therapy" aims to harness nanotechnology and interdisciplinary approaches to modify nanocarriers to enable precise targeting. Moreover, engineering responsive nanocarriers to release payloads at the right moment will maximize therapeutic impact while minimizing side effects.

This Research Topic seeks to explore the innovative realm of engineered nanocarriers in biomedical applications, focusing on precise imaging and targeted therapy. We invite contributions that delve into the following themes:
•Nanocarrier design and fabrication: manuscripts exploring novel techniques and materials used in engineering nanocarriers, emphasizing their biocompatibility and scalability.
•Targeted drug delivery: research elucidating strategies for encapsulating therapeutic agents within nanocarriers, ensuring targeted and controlled drug release for enhanced efficacy and reduced side effects.
•Responsive nanocarriers: investigations into smart nanocarriers that respond to physiological cues (such as pH, temperature, or enzymatic activity) for site-specific drug delivery, maximizing precision.
•Biomedical imaging enhancement: studies focused on incorporating contrast agents within nanocarriers to improve the sensitivity and specificity of imaging techniques like MRI, CT, and ultrasound.
•Pre-clinical Studies and Applications: Manuscripts detailing in vivo experiments showcasing the potential real-world effectiveness and safety of engineered nanocarriers in biomedical imaging and therapy.

Keywords: Nanotechnology, Drug Delivery, Therapeutics, Theranostics, Precision Medicine

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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