A renal biopsy is one of the cornerstones in the clinical management of patients with kidney disease. An accurate assessment of the specimen supports differential diagnosis, provides important information to assess the severity of the disease, and paves the way for tailored treatment. Unfortunately, the procedure is considered invasive and therefore many clinicians have a restrictive approach.
Recent evidence increasingly shows a higher inter-individual variability of prognosis and response to therapy of individuals with kidney disease despite a seemingly identical clinical phenotype (at least as judged with current means). In this respect even more important information could be obtained from biopsy tissue, allowing us to better (sub)-classify individual disease entities and phenotypes. On the contrary, this will demand continuous improvement in the biopsy workup.
This special issue of Frontiers in Nephrology looks for contributions that expand our knowledge and understanding of the role of renal biopsies in clinical practice as well as experimental research.
Keywords:
renal biopsy, glomerulonephritis, nephrotic syndrome, transplant, podocyte
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
A renal biopsy is one of the cornerstones in the clinical management of patients with kidney disease. An accurate assessment of the specimen supports differential diagnosis, provides important information to assess the severity of the disease, and paves the way for tailored treatment. Unfortunately, the procedure is considered invasive and therefore many clinicians have a restrictive approach.
Recent evidence increasingly shows a higher inter-individual variability of prognosis and response to therapy of individuals with kidney disease despite a seemingly identical clinical phenotype (at least as judged with current means). In this respect even more important information could be obtained from biopsy tissue, allowing us to better (sub)-classify individual disease entities and phenotypes. On the contrary, this will demand continuous improvement in the biopsy workup.
This special issue of Frontiers in Nephrology looks for contributions that expand our knowledge and understanding of the role of renal biopsies in clinical practice as well as experimental research.
Keywords:
renal biopsy, glomerulonephritis, nephrotic syndrome, transplant, podocyte
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.