Function of Vestibular and Auditory Systems in Neurogenerative Disorders

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About this Research Topic

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Background

The vestibular and auditory systems play pivotal roles in maintaining balance, spatial orientation, and hearing. Recent studies have shed light on the connection between dysfunction in these sensory systems and the onset or progression of neurogenerative disease, including but not limited to Alzheimer's disease, Parkinson's disease, and multiple sclerosis. A globally growing number of people affected by neurogenerative disorders encourages scientists to look for new innovative markers of early onset of neurogenerative diseases. Recent studies suggest central vestibular and auditory processing impairments could manifest many years before clinical diagnosis. For instance, it has been shown that if the severity of peripheral hearing loss increases from mild to severe, the dementia risk also increases from double to five times. Many individuals with neurogenerative diseases experience impaired balance, making it challenging to maintain postural stability and increasing the risk of falls.

We are pleased to announce a call for manuscripts for our Research Topic, focusing on exploring the function/dysfunction of vestibular and auditory systems in neurogenerative diseases. A primary goal of the Research Topic is understanding how vestibular and auditory system dysfunction contributes to neurodegeneration. We aim to provide a platform for studies that elucidate the complex interactions between vestibular and auditory systems and the development of various neurogenerative diseases using different experimental approaches in animal models and human subjects. This Research Topic aims to identify specific biomarkers within the vestibular and auditory systems that could serve as early indicators or diagnostic tools for neurogenerative diseases. The discovery of such markers could lead to earlier detection of disease onset, potentially enabling timely and successful intervention.

We welcome submissions of manuscripts that report Original Research, Review, Clinical Studies, Case Reports, Methods, or Computational Models that delve into, but are not limited to, the following topics:

• Vestibular Dysfunction: Investigate the impact of vestibular system dysfunction on neurodegenerative diseases and its potential role as a biomarker for early diagnosis.

• Auditory Impairment: Examine the correlation between auditory system dysfunction and cognitive decline associated with neurogenerative conditions.

• Diagnostic and Prognostic Markers: Research on biomarkers or diagnostic tools that can aid in the early detection and monitoring of neurodegenerative diseases based on vestibular and auditory assessments.

• Treatment and Rehabilitation Strategies: Exploration of therapeutic approaches, including vestibular rehabilitation and auditory interventions, for enhancing the quality of life for patients with neurodegenerative conditions.

• Animal Models and Translational Research: Research findings from animal models and translational studies that bridge the gap between basic science and clinical application.

• Clinical Case Studies: In-depth case studies providing insights into the practical challenges and successes encountered in managing patients

Keywords: Alzheimer's disease, Parkinson's disease, balance, hearing, auditory, MRI, electrophysiology

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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