Advances in Therapeutic Gastrointestinal Endoscopy: from Bench to Bedside

Gastrointestinal diseases have long presented significant challenges for both patients and healthcare providers. However, the field of gastrointestinal endoscopy has experienced remarkable advancements that have revolutionized diagnosis, treatment, and patient care. The concept of minimally invasive endoscopic techniques, and even super-minimally invasive techniques, has gained prominence in clinical practice and scientific discourse. Recent years have witnessed the emergence of new technologies, improved imaging capabilities, increased rates of cancer screening, and changes in public perceptions towards disease management, all of which have fundamentally transformed the approach to managing both benign and malignant gastrointestinal conditions. A growing body of evidence supports the efficacy and safety of procedures such as endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) for the treatment of precancerous conditions, early-stage cancers, and lesions located within the mucosa or submucosa layers. Techniques like endoscopic full thickness resection (EFTR) allow for complete tumor removal by accessing deeper tissues. Submucosal tunneling endoscopic resection (STER) has gained widespread clinical acceptance, representing a direct evolution of the endoscopic tunneling technique. Additionally, peroral endoscopic myotomy (POEM) shows promising outcomes in the treatment of achalasia. Lumen-apposing metal stents (LAMS) are explored as potential treatments for gastrointestinal tract strictures, facilitating the creation of anastomoses. Moreover, ongoing research focuses on various other aspects, including endoscopic ultrasound-guided procedures (such as pancreatic pseudocyst drainage and alcoholization), novel endoscopic retrograde cholangiopancreatography (ERCP) approaches, endoscopic bariatric interventions, and gastrointestinal wall closure techniques.

This Research Topic aims to shed light on the latest advancements in therapeutic gastrointestinal endoscopy. We invite original research contributions and comprehensive reviews that cover diverse aspects of this field, fostering the dissemination of knowledge and driving further developments. Researchers and clinicians are encouraged to share their insights and findings to enhance our understanding and improve patient care in the realm of gastrointestinal diseases. We welcome submissions with a focus on, but not limited to, the following subtopics:
- Research on digestive endoscopic tunnel technique and their underlying mechanisms, including peroral endoscopic myotomy (POEM), submucosal tunneling endoscopic resection (STER), endoscopic submucosal tunnel
dissection (ESTD)
- Research on endoscopic submucosal dissection (ESD) and full-thickness endoscopic resection with their underlying mechanisms
- Research on Endoscopic retrograde cholangiopancreatography (ERCP) and Single-operator peroral cholangioscopy system
- Novel advances in therapeutic endoscopic ultrasound (EUS)
- Novel endoscopic approaches in the management of gastrointestinal bleeding and perforation
- Endoscopic bariatric procedures with the underlying mechanisms of it
- Artificial intelligence in therapeutic Gastrointestinal Endoscopy