Emerging Applications of Targeted and Non-Targeted Metabolomics to Physiology and Pathophysiology

Metabolomics is one of the ‘omics’ approaches that involve high-throughput identification and quantification of small chemical compounds (<1000 to 1500 Da), present in a variety of biological systems such as a cell, an organism, or biological fluids. The metabolome includes endogenous (e.g., amino acids, fatty acids, sugars, carbohydrates, vitamins, lipids, and their derivatives) as well as exogenous (e.g., pollutants, pharmaceuticals, food additives, xenobiotics) compounds.

The targeted and untargeted application of metabolomics to physiology can help with a rapid screening of the majority of metabolites and detect potential changes in their concentrations leading to a better understanding of complex physiological, biological and biochemical interactions in various models.

This Research Topic aims to highlight mass spectrometry and/or NMR applications of physiological samples in various fields of physiology.

Metabolomics studies pertinent to all areas of physiology and pathophysiology in cell, animal and human models specifically studies related to cell physiology, metabolic physiology, mitochondrial physiology, lipids and fatty acids research are invited to submit their original data to this Research Topic.