About this Research Topic
Although cancer nanotherapeutics have made remarkable headway in treating a variety of cancers in clinical trials, little progress has been made in the pancreatic cancer field. Although nanodelivery of chemotherapeutic agents initially showed promising results in animal studies, the prognosis for pancreatic patients has not significantly improved. This is thought to be largely due to chemotherapeutic resistance caused by pancreatic cancer stem cells.
We propose that generating novel nanoparticles that both target pancreatic cancer stem cells, while delivering chemotherapeutic drug(s), would be more effective at reducing tumor load, invasiveness, and drug resistance, thus improving the prognosis of pancreatic cancer patients.
This Research Topic seeks to investigate novel treatments for pancreatic cancer, whether testing new drugs, or using novel combinations of drugs with commonly used therapeutics. We welcome contributions spanning a wide range of topics, including but not limited to nanotherapeutics, pancreatic cancer, pancreatic cancer stem cells, pancreatic cancer vaccines, and novel cell or animal models.
We welcome the following article types: Brief Research Report, Case Report, Clinical Trial, Correction, Hypothesis & Theory, Methods, Original Research, Policy and Practice Reviews, Study Protocol, Systematic Review, and Technology and Code.
Keywords: Nanoparticles, Pancreatic Cancer, Cancer Stem Cells, Immunotherapy-Resistance
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