About this Research Topic
The gut microbiome plays an important role in host health, immunity, nutrient use, and stress response, and there is a perceivable link between the host genotype and the gut microbiome. Currently, we only have a limited understanding of the impact of host genetics and nutrition on the structure and function of the gut microbiome as well as the spatiotemporal development of the gut microbial community.
Although the microbiome in the gut is the most studied, commensal microbiomes also reside in many other anatomic sites of livestock species, such as the skin, the respiratory and reproductive tracts, and may impact host physiology far beyond the gut. Our current knowledge is scarce for microbial communities in non-gut organs or tissues of livestock species. There is a growing need to identify and characterize commensal microbiomes at different sites of livestock and how they are shaped by host genetics. Computational and statistical tools to model the interactions between the microbiome and its host are also lacking.
In this Research Topic, we welcome the submission of Original Research and Review articles focused on, but not limited to, the following areas.
- Spatiotemporal development of the microbiomes of different anatomical sites and potential correlation with host transcriptomes
- Impact of host genetics on the structure and function of the commensal microbiome
- Computational tools that enable quick genotyping of the gut microbial community
- Statistical methods to help correlate microbial profiles with host metabolic activities by taking the environmental factors into account
- The heritable core microbiomes in different segments of the intestinal tract
- The role of neonatal dietary intervention in the structure and function of the gut microbiome
- Characterization of microbial dysbiosis in different disease states
- Convenient microbial biomarkers that enable real-time assessment of the gut microbial community
- Functional roles of individual microbes in host health, disease, and production efficiency
- High-quality microbial genomes and transcriptomes and functional annotation of uncultured microbes
- Development of databases that include microbial community composition, genome assembly, and host phenotypic information
Although the microbiome in the gut is the most studied, commensal microbiomes also reside in many other anatomic sites of livestock species, such as the skin, the respiratory and reproductive tracts, and may impact host physiology far beyond the gut. Our current knowledge is scarce for microbial communities in non-gut organs or tissues of livestock species. There is a growing need to identify and characterize commensal microbiomes at different sites of livestock and how they are shaped by host genetics. Computational and statistical tools to model the interactions between the microbiome and its host are also lacking.
In this Research Topic, we welcome the submission of Original Research and Review articles focused on, but not limited to, the following areas.
- Spatiotemporal development of the microbiomes of different anatomical sites and potential correlation with host transcriptomes
- Impact of host genetics on the structure and function of the commensal microbiome
- Computational tools that enable quick genotyping of the gut microbial community
- Statistical methods to help correlate microbial profiles with host metabolic activities by taking the environmental factors into account
- The heritable core microbiomes in different segments of the intestinal tract
- The role of neonatal dietary intervention in the structure and function of the gut microbiome
- Characterization of microbial dysbiosis in different disease states
- Convenient microbial biomarkers that enable real-time assessment of the gut microbial community
- Functional roles of individual microbes in host health, disease, and production efficiency
- High-quality microbial genomes and transcriptomes and functional annotation of uncultured microbes
- Development of databases that include microbial community composition, genome assembly, and host phenotypic information
Keywords: Host genetics, microbiome, health, disease, livestock
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
