About this Research Topic
This Research Topic aims to consolidate research findings concerning the use of herbal medicine and plant extracts in treating arrhythmias. The primary objective is to enhance clinicians' understanding of these interventions, enabling them to deliver personalized care to arrhythmia patients. Additionally, the special issue endeavors to provide a research foundation for the development of novel antiarrhythmic drugs. By addressing gaps in knowledge and identifying recent breakthroughs, this Research Topic seeks to elucidate the potential of herbal medicine and plant extracts in arrhythmia treatment.
This Research Topic encompasses a comprehensive exploration of herbal medicine and plant extracts in the context of arrhythmia treatment. Authors are encouraged to contribute manuscripts focusing on various themes, including but not limited to:
• Elucidating the biological mechanisms underlying the anti-arrhythmic effects of herbal medicine.
• Identifying novel active compounds within herbal medicine for the treatment of arrhythmias.
• Presenting clinical studies that assess the therapeutic efficacy of herbal medicine in managing arrhythmias.
We invite a diverse range of manuscript types, such as Perspective, Original Research, Review, Commentary, Opinion, Clinical Trial, and Case Report, to shed light on the multifaceted aspects of herbal interventions in arrhythmia treatment. This Research Topic serves as a platform to disseminate cutting-edge research and expand our understanding of these promising therapeutic strategies.
Please note the following:
1) All studies must use a therapeutically realistic dose level, and the data must be reported on the basis of the amount of extract administered. Single-dose studies are not accepted unless they focus on a species/compound not yet studied in detail and can be justified on specific ethical grounds (e.g. the 4R rule - Reduce, refine, replace – responsibility, see the Four Pillars).
2) A detailed chemical profile of the extract and pharmacognostic definition of the botanical drugs used is essential, as defined in the ConPhyMP statement 2022 (Front. Pharmacol. 13:953205.)
3 ) Traditional context - The traditional context must be described in the introduction and supported with bibliographical primary references (see also Section 3 esp. 3d - traditional medicinal preparations and their assessment). This may be based on modern uses of a plant in general healthcare.
4 ) Clinical trial articles will be accepted for review only if they are randomized, double-blinded, and placebo controlled. Statistical power analysis or a justification of the sample size is mandatory as is a detailed chemical characterization of the study medication (see the ConPhyMP statement).
5) All the manuscripts submitted to this project will be peer-reviewed and need to fully comply with the Four Pillars of Best Practice in Ethnopharmacology Four Pillars of Best Practice in Ethnopharmacology (you can freely download the full version here). Importantly, please ascertain that the ethnopharmacological context is clearly described (pillar 3d) and that the material investigated is characterized in detail (pillars 2 a and b).
Keywords: Herbal Medicine, arrhythmia, electrophysiology, cardiovascular diseases
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.