About this Research Topic
This Research Topic aims to explore the intricate cellular mechanisms that contribute to hearing loss. We invite researchers to investigate the molecular and cellular changes occurring in various types of hearing loss, unraveling the pathophysiological processes that disrupt auditory function. Investigations could focus on the involvement of specific cell types such as hair cells, spiral ganglion neurons, supporting cells, and immune cells in the cochlea. Additionally, contributions elucidating the role of synaptic function, inflammation, oxidative stress, and neurotrophic factors in the cellular neuropathology of hearing loss are also welcome.
Furthermore, studies involving animal models, cell cultures, stem cell therapy, and innovative imaging techniques are encouraged. The use of cutting-edge approaches, such as single-cell transcriptomics, proteomics and metabolomics, optogenetics, and 3D imaging, can provide novel insights into the cellular alterations underlying hearing loss.
This Research Topic welcomes Original Research, Reviews, Mini-Review, Hypothesis and Theories, Perspectives, and Opinion articles, with the aim of assembling a comprehensive collection of studies shedding light on the cellular neuropathology of hearing loss.
Topic Editor Marisa Zallocchi holds three patents for compounds potentially protective in hearing loss. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Keywords: hearing loss, hair cells, ganglion neurons, cochlea, neuropathology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.