About this Research Topic
Gestational diabetes mellitus (GDM) is a temporary form of diabetes that occurs during pregnancy, frequently from the 24th to 28th week of gestation. The incidence of this type of diabetes is increasing worldwide, leading to significant morbidity for both the mother and the offspring. Indeed, GDM is associated with adverse pregnancy outcomes and long-term health consequences, such as an increased risk of developing type 2 diabetes later in life. Although improvements in GDM knowledge have been made, evidence gaps persist at all points, from early prediction to long-term follow-up. Research should delve into refining risk prediction by incorporating novel biomarkers, genetic markers, and other predictive tools allowing for effective preventive strategies. Furthermore, further research is needed to comprehensively study the long-term consequences of GDM for both mothers and their offspring, including the potential for intergenerational transmission of diabetes risk.
The goal of this Research Topic is to bring together a collection of papers that individually and collectively use a translational approach to provide an overview of the status and outlook of advances in GDM research. These insights will identify potential novel biomarkers for risk prediction of GDM development and complications for both mothers and offspring.
We welcome the submission of manuscripts including, but not limited to, the following topics:
• Novel biomarkers for GDM risk prediction:
- Serum biomarkers for the prediction of GDM development;
- Serum biomarkers for risk stratification of GDM complications;
- Genetic or epigenetic signatures for risk prediction of GDM development and complications;
- Other predictive tools allowing for effective preventive and therapeutic strategies during prenatal care.
• Risk models and therapeutic approaches for long-term complications:
- Cohort and population studies aimed at identifying predictive variables for long term outcomes of GDM;
- Clinical studies evaluating the efficacy of different therapeutic approaches on GDM incidence and complications.
The goal of this Research Topic is to bring together a collection of papers that individually and collectively use a translational approach to provide an overview of the status and outlook of advances in GDM research. These insights will identify potential novel biomarkers for risk prediction of GDM development and complications for both mothers and offspring.
We welcome the submission of manuscripts including, but not limited to, the following topics:
• Novel biomarkers for GDM risk prediction:
- Serum biomarkers for the prediction of GDM development;
- Serum biomarkers for risk stratification of GDM complications;
- Genetic or epigenetic signatures for risk prediction of GDM development and complications;
- Other predictive tools allowing for effective preventive and therapeutic strategies during prenatal care.
• Risk models and therapeutic approaches for long-term complications:
- Cohort and population studies aimed at identifying predictive variables for long term outcomes of GDM;
- Clinical studies evaluating the efficacy of different therapeutic approaches on GDM incidence and complications.
Keywords: Gestational diabetes, Pregnancy complications, Obstetric Medicine
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
