Targeting Mitochondrial Dysfunction for the Discovery and Development of Novel CNS Therapies in Rare and Neurodegenerative Diseases

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ORIGINAL RESEARCH

Published on 09 Apr 2025

Interpreting the clinical significance of multiple large-scale mitochondrial DNA deletions (MLSMD) in skeletal muscle tissue in the diagnostic evaluation of primary mitochondrial disease

Jing Wang
James T. Peterson
Joaquim Diego D. Santos
Ada J. S. Chan
Maria Alejandra Diaz-Miranda
Imon Rahaman
Jean Flickinger
Amy Goldstein
Emily Bogush
8 more
Zarazuela Zolkipli-Cunningham

doi 10.3389/fphar.2025.1507493

627 views

SYSTEMATIC REVIEW

Published on 07 Apr 2025

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

Long-yun Zhou
Xiao-bo Wang
Xu-qing Chen
Ran Li
Bin-bin Yu
Meng-xiao Pan
Lu Fang
Jian Li
Xue-jun Cui
1 more
Xiao Lu

doi 10.3389/fphar.2025.1538879

276 views

REVIEW

Published on 19 Mar 2025

Mitochondria and oxidative stress in epilepsy: advances in antioxidant therapy

Delphine Ji
Shanthini Mylvaganam
Prathyusha Ravi Chander
Mark Tarnopolsky
Keiran Murphy
Peter Carlen

doi 10.3389/fphar.2024.1505867

693 views

REVIEW

Published on 07 Jan 2025

Nature’s magic: how natural products work hand in hand with mitochondria to treat stroke

Lin Cheng
Shangbin Lv
Chengkai Wei
Sucheng Li
Hao Liu
Yong Chen
Zhaoliang Luo
Hongyan Cui

doi 10.3389/fphar.2024.1434948

1,128 views
1 citation

MINI REVIEW

Published on 02 Oct 2024

Autophagy is a promising process for linking inflammation and redox homeostasis in Down syndrome

Xuehai Ma
Weimin Li
Jun Ma
Zhongcheng Han
Shoulong Deng
Sutian Wang

doi 10.3389/fphar.2024.1491563

610 views
1 citation

ORIGINAL RESEARCH

Published on 06 Aug 2024

YAP activation in Müller cells protects against NMDA-induced retinal ganglion cell injury by regulating Bcl-xL expression

Toshihide Kashihara
Yui Morita
Misaki Hatta
Sae Inoue
Yume Suzuki
Akane Morita
Tsutomu Nakahara

doi 10.3389/fphar.2024.1446521

1,198 views
1 citation

REVIEW

Published on 25 Jul 2024

The interplay between mitochondria, the gut microbiome and metabolites and their therapeutic potential in primary mitochondrial disease

Kassandra A. Zachos
Jann Aldrin Gamboa
Aleena S. Dewji
Jocelyn Lee
Sonya Brijbassi
Ana C. Andreazza

doi 10.3389/fphar.2024.1428242

2,404 views
3 citations

BRIEF RESEARCH REPORT

Published on 17 Apr 2024

Epigenetic alterations in creatine transporter deficiency: a new marker for dodecyl creatine ester therapeutic efficacy monitoring

Léa Broca-Brisson
Clémence Disdier
Rania Harati
Rifat Hamoudi
Aloïse Mabondzo

doi 10.3389/fnins.2024.1362497

1,906 views

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Neuropharmacology

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Frontiers in Neuroscience
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Articles

Interpreting the clinical significance of multiple large-scale mitochondrial DNA deletions (MLSMD) in skeletal muscle tissue in the diagnostic evaluation of primary mitochondrial disease

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

Mitochondria and oxidative stress in epilepsy: advances in antioxidant therapy

Nature’s magic: how natural products work hand in hand with mitochondria to treat stroke

Autophagy is a promising process for linking inflammation and redox homeostasis in Down syndrome

YAP activation in Müller cells protects against NMDA-induced retinal ganglion cell injury by regulating Bcl-xL expression

The interplay between mitochondria, the gut microbiome and metabolites and their therapeutic potential in primary mitochondrial disease

Epigenetic alterations in creatine transporter deficiency: a new marker for dodecyl creatine ester therapeutic efficacy monitoring

Frontiers in Pharmacology

Neuropharmacology

Participating Journals

Frontiers in Neuroscience

Neuropharmacology