About this Research Topic
Intracerebral Hemorrhage (ICH) is the most lethal subtype of stroke, representing approximately 10-20% of all stroke subtypes. The recently released 2022 American Heart and Stroke Association Guidelines provide practice guidelines and updates for the evaluation and management of patients with acute ICH. The current guideline acknowledges a number of limitations and knowledge gaps pertaining to neuro imaging in acute ICH. In this research topic, we explore current knowledge gaps, controversies and limitations related to the neuro imaging diagnosis, monitoring and evaluation of patients with acute ICH.
The goal of this research topic is to:
1- Explore neuro imaging markers and advance in neuro imaging that may predict hematoma expansion (HE) and/or clinical worsening
2- Explore newest imaging approaches to ICH that may differentiate primary ICH from secondary causes.
3- Describe current research that evaluate cost/benefit implications of serial imaging after ICH and clarify the patient characteristics and conditions under which serial imaging should be considered.
4- Describe the utility of NCCT signs to predict HE, alone or as part of prediction scores based on clinical variables, and guide decision-making on the triage and monitoring of patients with ICH at high risk for HE.
5- Refine the utility of NCCT signs (defined by standardized criteria) and HE scores to maximize their diagnostic and predictive capabilities and validity.
6- Evaluate the diagnostic performance of noninvasive neuroimaging to reveal the underlying cause of ICH.
7- Incorporate diagnostic criteria that include molecular fluid-based and imaging-based biomarkers such as β-amyloid in the evaluation and management of ICH
8- Incorporate multimodality scoring application of other baseline biomarkers (imaging, fluid, and/or electrophysiology based) to outcome prediction, and validate the utility of best practices for using severity scores in patient/caregiver communication and shared decision-making.
We welcome original research, reviews, perspectives, and case series.
The goal of this research topic is to:
1- Explore neuro imaging markers and advance in neuro imaging that may predict hematoma expansion (HE) and/or clinical worsening
2- Explore newest imaging approaches to ICH that may differentiate primary ICH from secondary causes.
3- Describe current research that evaluate cost/benefit implications of serial imaging after ICH and clarify the patient characteristics and conditions under which serial imaging should be considered.
4- Describe the utility of NCCT signs to predict HE, alone or as part of prediction scores based on clinical variables, and guide decision-making on the triage and monitoring of patients with ICH at high risk for HE.
5- Refine the utility of NCCT signs (defined by standardized criteria) and HE scores to maximize their diagnostic and predictive capabilities and validity.
6- Evaluate the diagnostic performance of noninvasive neuroimaging to reveal the underlying cause of ICH.
7- Incorporate diagnostic criteria that include molecular fluid-based and imaging-based biomarkers such as β-amyloid in the evaluation and management of ICH
8- Incorporate multimodality scoring application of other baseline biomarkers (imaging, fluid, and/or electrophysiology based) to outcome prediction, and validate the utility of best practices for using severity scores in patient/caregiver communication and shared decision-making.
We welcome original research, reviews, perspectives, and case series.
Keywords: Intracerebral Hemorrhage, neuro-imaging, Hemorrhagic Stroke, Acute Stroke, Intraparenchymal hemorrhage
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
