When The Drug Induces Kidney Diseases: Nephrotoxicity and Intoxication/Poisoning

Drug-induced nephrotoxicity in adults is approximately 14%–26% in prospective cohort studies of AKI, whereas 16% of hospitalized AKI are due to drugs in the paediatric population. Our knowledge of the epidemiology of nephrotoxicity focuses predominantly on drug-induced AKI. The epidemiology of tubular disorders is unclear, as a standard definition is lacking. Glomerular injury is uncommon, and most literature is limited to case reports or case series. Poisoning can occur from various exposures, including medicines, chemicals, or natural toxins from animals or plants. Each scenario potentially manifests differently, which in turn prompts different approaches to management. The clinical application of extracorporeal treatments, such as hemodialysis or hemoperfusion, is used to facilitate the elimination of many poisons, albeit with uncertain clinical benefits.

This Research Topic aims to gather quality content about drug induced nephrotoxicity and its impact on morbidity and mortality, renal outcomes, prevention, electronic alerts, use of artificial intelligence and machine learning, the indication of extracorporeal toxin removal, and advances in the subject.

This Research Topic "When the drug induces kidney diseases: nephrotoxicity and intoxication/poisoning". It will accept case reports and case series, original studies, pharmacokinetic/pharmacodynamic studies, clinical trials, and narrative and systematic reviews.