About this Research Topic
Craniofacial defects encompass a range of deformities affecting the skull, facial bones, and soft tissues, often resulting from trauma, genetic diseases, or abnormal embryonic development. These defects can have severe implications, including intellectual disability and visual impairment, necessitating functional reconstruction for optimal patient outcomes. However, despite extensive research in both clinical and basic sciences, the development of novel and effective strategies for craniofacial defect reconstruction remains an ongoing challenge.
To address this gap in knowledge, we invite original research, case reports, and review papers that explore various aspects of functional reconstruction for craniofacial defects. Specifically, we seek contributions that delve into the following areas:
-Advanced clinical investigations, showcasing current functional reconstruction strategies and surgical techniques, and their efficacy in treating craniofacial defects
-Cell biology and biomedical technology for reconstructing craniofacial defects
-Immunotherapeutic strategy to manipulate oral inflammation-caused craniofacial defects, such as maxillofacial bone loss, craniofacial muscle fibrosis, facial skin scar, etc
-Application of computational technology, artificial intelligence, and additive manufacturing technology in treating craniofacial defects, including the defects that happen after oral oncology treatment.
-Advancements in basic science research, investigating the genetic changes, etiology, and pathogenesis of craniofacial defects to facilitate the exploration of new therapeutic strategies.
-Other related research and reviews that contribute to our understanding of craniofacial defects and their management.
By collating and sharing the latest insights in this field, we aim to accelerate progress in functional reconstruction, ultimately improving the quality of life for individuals with craniofacial defects.
To address this gap in knowledge, we invite original research, case reports, and review papers that explore various aspects of functional reconstruction for craniofacial defects. Specifically, we seek contributions that delve into the following areas:
-Advanced clinical investigations, showcasing current functional reconstruction strategies and surgical techniques, and their efficacy in treating craniofacial defects
-Cell biology and biomedical technology for reconstructing craniofacial defects
-Immunotherapeutic strategy to manipulate oral inflammation-caused craniofacial defects, such as maxillofacial bone loss, craniofacial muscle fibrosis, facial skin scar, etc
-Application of computational technology, artificial intelligence, and additive manufacturing technology in treating craniofacial defects, including the defects that happen after oral oncology treatment.
-Advancements in basic science research, investigating the genetic changes, etiology, and pathogenesis of craniofacial defects to facilitate the exploration of new therapeutic strategies.
-Other related research and reviews that contribute to our understanding of craniofacial defects and their management.
By collating and sharing the latest insights in this field, we aim to accelerate progress in functional reconstruction, ultimately improving the quality of life for individuals with craniofacial defects.
Keywords: craniofacial defects, genetic disease, embryonic development, trauma
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
