Variability in Body Weight and the Risk of Cardiovascular Complications in Type 2 Diabetes

Diabetes mellitus is a global health burden accounting for increased hospitalization, morbidity and mortality. High body weight variability is closely linked to diabetes, and can be caused by family/genetic history, environment, behavioral and poor nutritional lifestyles among other factors. Increase body weight variability does not only increase an individual’s risk of developing Type 2 Diabetes Mellitus (T2DM), but also increases the risk of microvascular and macrovascular complications especially cardiometabolic and cardiovascular diseases (CVDs). CVDs – such as ischemic heart attack, cerebrovascular accident (Stroke), fatal myocardial infarction, heart failure (HF), coronary artery disease (CAD), and peripheral artery disease– are the main cause of death among people with diabetes mellitus. Additionally, poor management of the diabetic condition can contribute to uncontrolled weight gain and aggravate the diabetes condition.

This Research Topic encourages all article types accepted by Frontiers that:
1) Identify the various risk factors of body weight variability among T2DM individuals and the subsequent implication of cardiovascular complications
2) Identify new measures of body weight as interventional and personalized strategies for cardiovascular disease prevention in Type 2 diabetes patients
3) Identify nutrition models influencing body-weight variability and cardio-metabolic outcomes in Type 2 diabetes patients.

Specific themes of interest include, but are not limited to:
• Novel measure of body weight variability and their predictive potential for cardiovascular complications
• Nutritional, behavioral and environment lifestyle risk factors for body weight in patients with Type 2 diabetes
• Lifestyle intervention for obesity in Type 2 diabetes
• Preventative measures relating to body weight and Type 2 diabetes
• Management of body weight in patients with Type 2 diabetes
• Poor glycemic control and risk of obesity
• Body weight and diabetes complications
• Cardiovascular diseases in Type 2 diabetes mellitus from losing weight to weight regain - clinical implications of weight cycling
• Pharmacological interventions to lose weight and weight cycling
• Dyslipidemia
• Nutrition models and cardiovascular outcomes in Type 2 Diabetes
• Nutrition models and metabolic outcomes in Type 2 Diabetes
• Nutrition Models and body weight variability in Type 2 Diabetes

Keywords: Diabetes Mellitus, Type 2 Diabetes, Body Weight Variability, Cardiovascular disease, Risk Factors, Nutrition, Behavior, Environment, Obesity

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.