Drug Development in Microbiology and Virology: from Structure, through Function Comprehension to Anti-Infectious Drugs

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ORIGINAL RESEARCH

Published on 31 Jul 2018

Investigating the Mechanism of Action of Diketopiperazines Inhibitors of the Burkholderia cenocepacia Quorum Sensing Synthase CepI: A Site-Directed Mutagenesis Study

Silvia Buroni
Viola C. Scoffone
Marco Fumagalli
Vadim Makarov
Maddalena Cagnone
Gabriele Trespidi
Edda De Rossi
Federico Forneris
Giovanna Riccardi
Laurent R. Chiarelli

Investigating the Mechanism of Action of Diketopiperazines Inhibitors of the Burkholderia cenocepacia Quorum Sensing Synthase CepI: A Site-Directed Mutagenesis Study

doi 10.3389/fphar.2018.00836

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22 citations

ORIGINAL RESEARCH

Published on 29 May 2017

An Antifungal Mechanism of Protolichesterinic Acid from the Lichen Usnea albopunctata Lies in the Accumulation of Intracellular ROS and Mitochondria-Mediated Cell Death Due to Apoptosis in Candida tropicalis

S. N. Kumar
C. Mohandas

doi 10.3389/fphar.2017.00301

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4 citations

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Frontiers in Pharmacology

Experimental Pharmacology and Drug Discovery

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