About this Research Topic
This is a continuation of the Research Topic on "Experimental Hernia Research from Bench to Bedside and Translational Perspectives".
The field of hernia research is a dynamic surgical area where new materials, agents, and operating techniques are continually being developed, implemented, and evaluated. Tissue engineering has already become a part of the clinical routine, largely due to well-defined outcome parameters such as recurrences, infection, pain, and patient comfort. However, there are still ongoing debates and gaps in knowledge, particularly in the area of cell-based therapies and new mesh concepts. The current state of research has produced significant studies, but there is a need for a better investigation into the translational value of these contributions.
The primary aim of this Research Topic is to collect dedicated works by renowned study groups and present the spectrum of current activities, from cell-based therapies to new mesh concepts. The research will focus on the translational value of each contribution, with authors strongly encouraged to describe their perception of a clinical problem as the starting point of their project. They will also be asked to speculate on the role of their research in later clinical use, including potential benefits over existing approaches and possible pitfalls.
The scope of this Research Topic is defined by the range of current activities in hernia research, with a particular focus on the translational value of each contribution. We welcome articles addressing, but not limited to, the following themes:
• Tissue engineering techniques for mesh and fixation devices;
• Stem cell or SVF therapies;
• Mesh infection;
• Animal models (standards, shortcomings of existing models in the light of new materials);
• Histological analysis (no agreement on standards, yet).
The field of hernia research is a dynamic surgical area where new materials, agents, and operating techniques are continually being developed, implemented, and evaluated. Tissue engineering has already become a part of the clinical routine, largely due to well-defined outcome parameters such as recurrences, infection, pain, and patient comfort. However, there are still ongoing debates and gaps in knowledge, particularly in the area of cell-based therapies and new mesh concepts. The current state of research has produced significant studies, but there is a need for a better investigation into the translational value of these contributions.
The primary aim of this Research Topic is to collect dedicated works by renowned study groups and present the spectrum of current activities, from cell-based therapies to new mesh concepts. The research will focus on the translational value of each contribution, with authors strongly encouraged to describe their perception of a clinical problem as the starting point of their project. They will also be asked to speculate on the role of their research in later clinical use, including potential benefits over existing approaches and possible pitfalls.
The scope of this Research Topic is defined by the range of current activities in hernia research, with a particular focus on the translational value of each contribution. We welcome articles addressing, but not limited to, the following themes:
• Tissue engineering techniques for mesh and fixation devices;
• Stem cell or SVF therapies;
• Mesh infection;
• Animal models (standards, shortcomings of existing models in the light of new materials);
• Histological analysis (no agreement on standards, yet).
Keywords: Hernia, Mesh, Cell-based Therapy, Animal Models, Tissue Engineering
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
