Low Anterior Resection Syndrome - Treatment Possibilities

The field of colorectal surgery has been grappling with the complex condition known as Low Anterior Resection Syndrome (LARS), which is characterized by bowel dysfunction following low anterior resection surgery. This syndrome significantly impacts the quality of life of rectal cancer patients, with up to 90% experiencing symptoms post-surgery. While symptoms tend to improve within one or two years, a significant proportion of patients continue to experience long-term dysfunction. The multifactorial etiology of LARS presents numerous challenges, making treatment difficult and prevention a key focus in managing this condition.

The primary aim of this Research Topic is to delve into the depths of LARS, with a specific emphasis on exploring new etiological theories and potential surgical treatments. We are particularly interested in clinical studies that shed light on various aspects related to this syndrome, including the efficacy of different treatment modalities and their impact on patients' quality of life.

To gather further insights into the etiology, prevention, and treatment of LARS, we welcome articles addressing, but not limited to, the following themes:

- Efficacy of transanal irrigation in managing bowel dysfunction in LARS patients;
- Potential benefits of sacral neuromodulation in alleviating symptoms and improving bowel function;
- Role of tibial neuromodulation in the treatment of LARS and its impact on patients' quality of life;
- Effectiveness of biofeedback therapy as an intervention to enhance bowel function;
- Innovative approaches to managing LARS.

We encourage submissions of various article types, including cohort studies, short communications, randomized controlled trials, and original articles.