About this Research Topic
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. The most studied risk factors for CVD development are unhealthy diet, physical inactivity, tobacco use, alcoholism, diabetes mellitus, obesity, and hypertension, among others. However, in recent years, alterations in oral healthcare have been associated with the development of non-infection of systemic disease, being the CVD one of the most prevalent. The association between oral health and systemic chronic diseases, such as CVD, is extremely complex. Among the proposed mechanisms of this association, systemic inflammation seems to play a central role. It has been suggested that oral inflammation induces a systemic inflammatory state that promotes or increases atherosclerotic plaque development and progression.
In recent years, the attention of scientists about the role of oral inflammation in the onset of CVD has increased. About oral diseases, periodontitis has a high prevalence of 45%–50% overall, being the sixth most common human disease, and its association with CVD has been established. This is an open field that requires further studies to elucidate underlying mechanisms and new therapeutic targets that allow the designing of new therapeutic options.
This Research Topic aims to publish a new articles about different oral diseases as risk factors for cardiovascular diseases, including animal models and clinical studies. A better understanding of the direct association between oral infection, inflammation, and cardiovascular disease is essential to the development of novel therapeutic approaches and strategies to improve oral health as well as total health.
We will consider original research articles, brief reports, case reports, and review articles focusing on, but not strictly limited to, the following topics:
-New systemic biomarkers associated with oral and cardiovascular diseases
-Oral microbiota and cardiovascular risk
-Periodontal disease, systemic inflammation, and the risk of cardiovascular disease.
-Diet, cardiovascular disease, and oral health.
In recent years, the attention of scientists about the role of oral inflammation in the onset of CVD has increased. About oral diseases, periodontitis has a high prevalence of 45%–50% overall, being the sixth most common human disease, and its association with CVD has been established. This is an open field that requires further studies to elucidate underlying mechanisms and new therapeutic targets that allow the designing of new therapeutic options.
This Research Topic aims to publish a new articles about different oral diseases as risk factors for cardiovascular diseases, including animal models and clinical studies. A better understanding of the direct association between oral infection, inflammation, and cardiovascular disease is essential to the development of novel therapeutic approaches and strategies to improve oral health as well as total health.
We will consider original research articles, brief reports, case reports, and review articles focusing on, but not strictly limited to, the following topics:
-New systemic biomarkers associated with oral and cardiovascular diseases
-Oral microbiota and cardiovascular risk
-Periodontal disease, systemic inflammation, and the risk of cardiovascular disease.
-Diet, cardiovascular disease, and oral health.
Keywords: Oral inflammation, periodontal diseases, cardiovascular diseases, gum disease, cardiovascular risk factors
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
