About this Research Topic
The World Health Organization (WHO) has set an ambitious goal to eliminate malaria in at least 30 countries by 2030, as part of the “Global Technical Strategy for Malaria 2016-2030”. The latest WHO data reported 249 million cases in 85 malaria endemic countries and 608,000 deaths. Current WHO projections estimate that key 2030 malaria incidence milestones will be missed by a staggering 89%.
Frontiers in Malaria recognizes the urgency of this global public health issue. We wish to acknowledge and support by launching a new annual special collection that highlights the efforts of researchers to combat the global malaria crisis.
This Research Topic is focused on highlighting some of the major contemporary threats to global malaria control, recognized by the WHO and key international donors, stakeholders and funders. Although two vaccines (RTS,S/AS01E and R21/Matrix-M) have been approved by the WHO, these are reserved for use in children only. The growing insecticide resistance is threatening to undermine the progress made in global malaria control. Therefore a novel, interdisciplinary toolkit to control malaria amongst all age groups and interrupt Anopheles transmission is urgently needed and represents a global priority for malaria elimination.
Topics that may be covered in this collection include, but are not limited to:
1. Vector insecticide resistance and new tools/insecticides to combat insecticide resistance:
• Novel molecular markers and mechanisms of insecticide resistance.
• Emerging resistance to ‘new’ vector control insecticides (including but not limited to PBO/pyrethroids, chlorfenapyr, pyriproxyfen, clothianidin).
• Phase I, II and III evaluations of novel vector control tools.
• Predictive mathematical models of insecticide resistance.
2. Residual malaria transmission
• Challenges to meeting malaria elimination targets in the Asia-Pacific Region.
• Operational monitoring of vector control tools in areas of high intervention coverage
• Monitoring and control of outdoor biting mosquitoes.
3. Novel strategies of pharmacological intervention
• Targets which are essential for the parasite or the mosquito.
• Tackling all developmental stages with either genetic tools or chemical compounds.
• Novel or repurposed drug entities against Plasmodium or the mosquito.
This Research Topic invites all authors with novel strategies to combat malaria in the third millennium including the parasite and the mosquito focusing on the listed issues. In particular, outstanding, scientific novelties should be anticipated. Original articles or reviews presenting recent scientific development and progress of a particular issue are welcome too.
We invite original research, opinion/perspective pieces and literature reviews (including systematic reviews).
Frontiers in Malaria recognizes the urgency of this global public health issue. We wish to acknowledge and support by launching a new annual special collection that highlights the efforts of researchers to combat the global malaria crisis.
This Research Topic is focused on highlighting some of the major contemporary threats to global malaria control, recognized by the WHO and key international donors, stakeholders and funders. Although two vaccines (RTS,S/AS01E and R21/Matrix-M) have been approved by the WHO, these are reserved for use in children only. The growing insecticide resistance is threatening to undermine the progress made in global malaria control. Therefore a novel, interdisciplinary toolkit to control malaria amongst all age groups and interrupt Anopheles transmission is urgently needed and represents a global priority for malaria elimination.
Topics that may be covered in this collection include, but are not limited to:
1. Vector insecticide resistance and new tools/insecticides to combat insecticide resistance:
• Novel molecular markers and mechanisms of insecticide resistance.
• Emerging resistance to ‘new’ vector control insecticides (including but not limited to PBO/pyrethroids, chlorfenapyr, pyriproxyfen, clothianidin).
• Phase I, II and III evaluations of novel vector control tools.
• Predictive mathematical models of insecticide resistance.
2. Residual malaria transmission
• Challenges to meeting malaria elimination targets in the Asia-Pacific Region.
• Operational monitoring of vector control tools in areas of high intervention coverage
• Monitoring and control of outdoor biting mosquitoes.
3. Novel strategies of pharmacological intervention
• Targets which are essential for the parasite or the mosquito.
• Tackling all developmental stages with either genetic tools or chemical compounds.
• Novel or repurposed drug entities against Plasmodium or the mosquito.
This Research Topic invites all authors with novel strategies to combat malaria in the third millennium including the parasite and the mosquito focusing on the listed issues. In particular, outstanding, scientific novelties should be anticipated. Original articles or reviews presenting recent scientific development and progress of a particular issue are welcome too.
We invite original research, opinion/perspective pieces and literature reviews (including systematic reviews).
Keywords: malaria, vector control, anopheles, plasmodium, drug resistance, drug targets, insecticide resistance
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
